| Company Name: |
3B Pharmachem (Wuhan) International Co.,Ltd.
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| Tel: |
821-50328103-801 18930552037 |
| Email: |
3bsc@sina.com |
| Products Intro: |
Product Name:PSB 36;1-Butyl-8-(hexahydro-2,5-Methanopentalen-3a(1H)-yl)-3,7-dihydro-3-(3-hydroxypropyl)-1H-purine-2,6-dione
CAS:524944-72-7
Purity:99% HPLC Package:1Mg ; 5Mg;10Mg ;100Mg;250Mg ;500Mg ;1g;2.5g ;5g ;10g
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| Company Name: |
EMMX Biotechnology LLC
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| Tel: |
888-539-0666 |
| Email: |
info@emmx.com |
| Products Intro: |
Product Name:PSB 36
CAS:524944-72-7
Purity:98% HPLC Package:5mg;10mg;25mg;50mg;100mg;250mg;500mg;1g
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| | 1-BUTYL-8-(HEXAHYDRO-2,5-METHANOPENTALEN-3A(1H)-YL)-3,7-DIHYDRO-3-(3-HYDROXYPROPYL)-1H-PURINE-2,6-DIONE Basic information |
| Product Name: | 1-BUTYL-8-(HEXAHYDRO-2,5-METHANOPENTALEN-3A(1H)-YL)-3,7-DIHYDRO-3-(3-HYDROXYPROPYL)-1H-PURINE-2,6-DIONE | | Synonyms: | PSB 36;1-BUTYL-8-(HEXAHYDRO-2,5-METHANOPENTALEN-3A(1H)-YL)-3,7-DIHYDRO-3-(3-HYDROXYPROPYL)-1H-PURINE-2,6-DIONE;1-Butyl-3-(3-hydroxypropyl)-8-(3-noradamantyl)xanthine;1-Butyl-8-(hexahydro-2,5-methanopentalen-3a(1H)-yl)-3,9-dihydro-3-(3-hydroxypropyl)-1H-purine-2,6-dione;1H-Purine-2,6-dione, 1-butyl-8-(hexahydro-2,5-methanopentalen-3a(1H)-yl)-3,9-dihydro-3-(3-hydroxypropyl)- | | CAS: | 524944-72-7 | | MF: | C21H30N4O3 | | MW: | 386.49 | | EINECS: | | | Product Categories: | | | Mol File: | 524944-72-7.mol |  |
| | 1-BUTYL-8-(HEXAHYDRO-2,5-METHANOPENTALEN-3A(1H)-YL)-3,7-DIHYDRO-3-(3-HYDROXYPROPYL)-1H-PURINE-2,6-DIONE Chemical Properties |
| Boiling point | 646.0±61.0 °C(Predicted) | | density | 1.304±0.06 g/cm3(Predicted) | | storage temp. | Desiccate at +4°C | | solubility | DMSO: ≥20mg/mL | | form | powder | | pka | 9.17±0.70(Predicted) | | color | white to tan | | InChI | 1S/C21H30N4O3/c1-2-3-5-25-18(27)16-17(24(20(25)28)6-4-7-26)23-19(22-16)21-11-13-8-14(12-21)10-15(21)9-13/h13-15,26H,2-12H2,1H3,(H,22,23)/t13-,14+,15-,21- | | InChIKey | CIBIXJYFYPFMTN-FZUGUKJMSA-N | | SMILES | CCCCN1C(=O)N(CCCO)c2nc([nH]c2C1=O)C34C[C@@H]5C[C@@H](C[C@H]3C5)C4 |
| WGK Germany | 3 | | Storage Class | 11 - Combustible Solids |
| | 1-BUTYL-8-(HEXAHYDRO-2,5-METHANOPENTALEN-3A(1H)-YL)-3,7-DIHYDRO-3-(3-HYDROXYPROPYL)-1H-PURINE-2,6-DIONE Usage And Synthesis |
| Uses | PSB36 was used to examine the role of A1-adenosine receptor-mediated cell signaling in CD39 expression in pancreatic b-cells of streptozotocin-induced diabetic mice. | | Definition | ChEBI: LSM-1748 is an oxopurine. | | Biological Activity | Potent and selective A 1 adenosine receptor antagonist. Displays binding affinities of 0.12, 187, 552, 6500 and 2300 nM for rA 1 , hA 2B , rA 2A , rA 3 and hA 3 receptors respectively. Demonstrates greater selectivity than DPCPX (8-Cyclopentyl-1,3-dipropylxanthine ). | | IC 50 | rA1: 0.12 nM (Ki); hA2B: 187 nM (Ki); rA2A: 552 nM (Ki); hA3: 2300 nM (Ki); rA3: 6500 nM (Ki) |
| | 1-BUTYL-8-(HEXAHYDRO-2,5-METHANOPENTALEN-3A(1H)-YL)-3,7-DIHYDRO-3-(3-HYDROXYPROPYL)-1H-PURINE-2,6-DIONE Preparation Products And Raw materials |
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