| Company Name: |
TargetMol Chemicals Inc.
|
| Tel: |
15002134094 |
| Email: |
marketing@targetmol.cn |
| Products Intro: |
Product Name:Metiazinic acid
CAS:13993-65-2
Package:25mg/RMB 10600;100mg/RMB 17500;50mg/RMB 13800
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| Company Name: |
Specs
|
| Tel: |
+31 15 251 8111 |
| Email: |
info@specs.net |
| Products Intro: |
Product Name:(10-methyl-10H-phenothiazin-2-yl)acetic acid
CAS:13993-65-2
Package:20mg
|
metiazinic acid manufacturers
- Metiazinic acid
-
- $1520.00 / 25mg
-
2026-01-04
- CAS:13993-65-2
- Min. Order:
- Purity:
- Supply Ability: 10g
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| | metiazinic acid Basic information |
| Product Name: | metiazinic acid | | Synonyms: | metiazinic acid;Metiazinic;(10-methyl-10H-phenothiazin-2-yl)acetic acid;(10-METHYL2-PHENOTHIAZINYL)ACETICACID;Ambrunate;Metian;Novartril;RP 16091 | | CAS: | 13993-65-2 | | MF: | C15H13NO2S | | MW: | 271.33 | | EINECS: | 2377950 | | Product Categories: | | | Mol File: | 13993-65-2.mol |  |
| | metiazinic acid Chemical Properties |
| Melting point | 146℃ | | Boiling point | 482.6±44.0 °C(Predicted) | | density | 1.2237 (rough estimate) | | refractive index | 1.7500 (estimate) | | pka | 4.12±0.10(Predicted) | | Water Solubility | 31mg/L(30 ºC) |
| Toxicity | LD50 in mice, rats (mg/kg): 800, ~500 orally (Joulou) |
| | metiazinic acid Usage And Synthesis |
| Originator | Soripan,Specia,France,1970 | | Definition | ChEBI: Phenothiazine substituted at nitrogen by a methyl group and at C-2 by a carboxymethyl group. | | Manufacturing Process | 10-Methyl-3-acetylphenthiazine is prepared in accordance with G. Cauquil and
A. Casadevall, Bull. Soc.Chim., p 768 (1955). (10-Methyl-3-phenthiazinyl)acetic acid (MP 146°C; 21.4 g) is prepared by Willgerodt's
reaction (action of sulfur and morpholine, followed by hydrolysis) employing
10-methyl-3-acetylphenthiazine as starting material. | | Therapeutic Function | Antiinflammatory | | Trade name | Roimal (Kantoishi, Japan),
Soripal (Torii, Japan). | | Synthesis | Metiazinic acid is prepared via
the Willgerodt reaction (sulfur and morpholine)
from 2-acetyl-10-methylphenothiazine.
 | | Dosage | Metiazinic acid has been beneficial to arthritis patients when given at a daily dose of
0.75 – 1.5 g/d. |
| | metiazinic acid Preparation Products And Raw materials |
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