| Company Name: |
Suzhou Chenrui Biotechnology Co. LTD
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| Tel: |
17625585511 |
| Email: |
1580084073@qq.com |
| Products Intro: |
Product Name:MC-Ala-Ala-PAB
CAS:1949793-44-5
Purity:95% Package:1g;5g;10g
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| Company Name: |
Affinity（Wuhan）Ltd.
|
| Tel: |
15841022315 |
| Email: |
sales@affinitytech.cn |
| Products Intro: |
Product Name:MC-Ala-Ala-PAB
CAS:1949793-44-5
Purity:>96% Package:100mg;1g;10g
|
| Company Name: |
Shaoyuan Technology (Shanghai) Co., Ltd.
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| Tel: |
021-50795510 4000665055 |
| Email: |
marketing@accelachem.com |
| Products Intro: |
Product Name:6-(2,5-Dioxo-2,5-dihydro-1-pyrrolyl)-N-[(S)-1-[[(S)-1-[[4-(hydroxymethyl)phenyl]amino]-1-oxo-2-propyl]amino]-1-oxo-2-propyl]hexanamide
CAS:1949793-44-5
Purity:>=95% Package:1g
|
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| | MC-Ala-Ala-PAB Basic information |
| Product Name: | MC-Ala-Ala-PAB | | Synonyms: | MC-Ala-Ala-PAB;6-(2,5-Dioxo-2,5-dihydro-1-pyrrolyl)-N-[(S)-1-[[(S)-1-[[4-(hydroxymethyl)phenyl]amino]-1-oxo-2-propyl]amino]-1-oxo-2-propyl]hexanamide | | CAS: | 1949793-44-5 | | MF: | C23H30N4O6 | | MW: | 458.51 | | EINECS: | | | Product Categories: | | | Mol File: | 1949793-44-5.mol |  |
| | MC-Ala-Ala-PAB Chemical Properties |
| Boiling point | 831.7±65.0 °C(Predicted) | | density | 1.287±0.06 g/cm3(Predicted) | | form | Solid | | pka | 13.48±0.70(Predicted) | | color | Light yellow to yellow |
| | MC-Ala-Ala-PAB Usage And Synthesis |
| Uses | MC-Ala-Ala-PAB is a cleavable ADC linker. Fmoc-Ala-Ala-PAB can be used in the synthesis of antibody-drug conjugates (ADCs)[1]. | | IC 50 | Cleavable Linker | | References | [1] Wayne C Widdison, et al. Development of Anilino-Maytansinoid ADCs that Efficiently Release Cytotoxic Metabolites in Cancer Cells and Induce High Levels of Bystander Killing. Bioconjug Chem. 2015 Nov 18;26(11):2261-78. DOI:10.1021/acs.bioconjchem.5b00430 |
| | MC-Ala-Ala-PAB Preparation Products And Raw materials |
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