| Company Name: |
Hangzhou Peptidego Biotech Co.,Ltd.
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| Tel: |
0571-87213919 |
| Email: |
Eric@peptidego.com |
| Products Intro: |
Product Name:Chemerin-9, mouse
CAS:686324-96-9
Purity:95% or 98% HPLC Package:1mg；5mg；10mg；50mg；100mg,1g or according to customer's detail requirement.
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L-Serine, L-phenylalanyl-L-leucyl-L-prolylglycyl-L-glutaminyl-L-phenylalanyl-L-alanyl-L-phenylalanyl- manufacturers
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| | L-Serine, L-phenylalanyl-L-leucyl-L-prolylglycyl-L-glutaminyl-L-phenylalanyl-L-alanyl-L-phenylalanyl- Basic information |
| | L-Serine, L-phenylalanyl-L-leucyl-L-prolylglycyl-L-glutaminyl-L-phenylalanyl-L-alanyl-L-phenylalanyl- Chemical Properties |
| Boiling point | 1456.3±65.0 °C(Predicted) | | density | 1.297±0.06 g/cm3(Predicted) | | storage temp. | Store at -20°C | | pka | 3.01±0.10(Predicted) | | Water Solubility | Soluble to 1 mg/ml in water | | Sequence | Phe-Leu-Pro-Gly-Gln-Phe-Ala-Phe-Ser |
| | L-Serine, L-phenylalanyl-L-leucyl-L-prolylglycyl-L-glutaminyl-L-phenylalanyl-L-alanyl-L-phenylalanyl- Usage And Synthesis |
| Description | Chemokine-like receptor 1 (CMKLR1) agonist (EC50 = 42 nM). Corresponds to C-terminal of full length mouse Chemerin, amino acids 148 - 156. | | Uses | Chemerin-9, mouse (Chemerin148-156, mouse) is a C-terminal nonapeptide of chemerin. Chemerin-9, mouse is a ligand for ChemR23 (EC50 = 42 nM). Chemerin-9, mouse reduces basal lipolysis in primary mouse white adipocytes(IC50 = 3.3 nM). Chemerin-9, mouse enhances memory and relieves Aβ1-42-induced memory impairment in AD mice. Chemerin-9, mouse also inhibits atherogenesis[1][2][3]. | | storage | Store at -20°C | | References | [1] Shimamura K, et al. Identification of a stable chemerin analog with potent activity toward ChemR23. Peptides. 2009 Aug;30(8):1529-38. DOI:10.1016/j.peptides.2009.05.030
[2] Sato K, et al. Chemerin-9, a potent agonist of chemerin receptor (ChemR23), prevents atherogenesis. Clin Sci (Lond). 2019 Aug 20;133(16):1779-1796. DOI:10.1042/CS20190336
[3] Lei Z, et al. Chemerin-9 Peptide Enhances Memory and Ameliorates Aβ1-42-Induced Object Memory Impairment in Mice. Biol Pharm Bull. 2020 Feb 1;43(2):272-283. DOI:10.1248/bpb.b19-00510 |
| | L-Serine, L-phenylalanyl-L-leucyl-L-prolylglycyl-L-glutaminyl-L-phenylalanyl-L-alanyl-L-phenylalanyl- Preparation Products And Raw materials |
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