2-Pyridinecarbonitrile, 5-[5-[4-[(1-methyl-4-piperidinyl)oxy]phenyl]-8-oxo-6-thioxo-5,7-diazaspiro[3.4]oct-7-yl]-3-(trifluoromethyl)-

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2-Pyridinecarbonitrile, 5-[5-[4-[(1-methyl-4-piperidinyl)oxy]phenyl]-8-oxo-6-thioxo-5,7-diazaspiro[3.4]oct-7-yl]-3-(trifluoromethyl)- Suppliers list
Company Name: Shanghai Beckham Medical Technology Co., Ltd  
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Company Name: TargetMol Chemicals Inc.  
Tel: 15002134094
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Company Name: Afflon Pharmaceutical (Sichuan) Co., Ltd.  
Tel: 17336178085
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Company Name: TargetMol Chemicals Inc.  
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2-Pyridinecarbonitrile, 5-[5-[4-[(1-methyl-4-piperidinyl)oxy]phenyl]-8-oxo-6-thioxo-5,7-diazaspiro[3.4]oct-7-yl]-3-(trifluoromethyl)- manufacturers

  • JNJ-pan-AR
  • JNJ-pan-AR pictures
  • $1520.00
  • 2026-05-11
  • CAS:1332390-06-3
  • Purity:
  • Supply Ability: 10g
2-Pyridinecarbonitrile, 5-[5-[4-[(1-methyl-4-piperidinyl)oxy]phenyl]-8-oxo-6-thioxo-5,7-diazaspiro[3.4]oct-7-yl]-3-(trifluoromethyl)- Basic information
Product Name:2-Pyridinecarbonitrile, 5-[5-[4-[(1-methyl-4-piperidinyl)oxy]phenyl]-8-oxo-6-thioxo-5,7-diazaspiro[3.4]oct-7-yl]-3-(trifluoromethyl)-
Synonyms:2-Pyridinecarbonitrile, 5-[5-[4-[(1-methyl-4-piperidinyl)oxy]phenyl]-8-oxo-6-thioxo-5,7-diazaspiro[3.4]oct-7-yl]-3-(trifluoromethyl)-;JNJ-pan-AR
CAS:1332390-06-3
MF:C25H24F3N5O2S
MW:515.55
EINECS:
Product Categories:
Mol File:1332390-06-3.mol
2-Pyridinecarbonitrile, 5-[5-[4-[(1-methyl-4-piperidinyl)oxy]phenyl]-8-oxo-6-thioxo-5,7-diazaspiro[3.4]oct-7-yl]-3-(trifluoromethyl)- Structure
2-Pyridinecarbonitrile, 5-[5-[4-[(1-methyl-4-piperidinyl)oxy]phenyl]-8-oxo-6-thioxo-5,7-diazaspiro[3.4]oct-7-yl]-3-(trifluoromethyl)- Chemical Properties
Boiling point 657.0±65.0 °C(Predicted)
density 1.47±0.1 g/cm3(Predicted)
pka8.16±0.10(Predicted)
Safety Information
MSDS Information
2-Pyridinecarbonitrile, 5-[5-[4-[(1-methyl-4-piperidinyl)oxy]phenyl]-8-oxo-6-thioxo-5,7-diazaspiro[3.4]oct-7-yl]-3-(trifluoromethyl)- Usage And Synthesis
DescriptionJNJ-pan-AR, a meylated analogue of JNJ-63576253, is a novel pan-AR antagonist with potent activity against wild-type and clinically relevant AR mutations including F877L. JNJ63576253, also known as TRC253, is a potent and orally active androgen receptor antagonist. TRC253 specifically binds to both wild-type and certain mutant forms of AR, thereby preventing androgen-induced receptor activation and facilitating the formation of inactive complexes that cannot translocate to the nucleus.
2-Pyridinecarbonitrile, 5-[5-[4-[(1-methyl-4-piperidinyl)oxy]phenyl]-8-oxo-6-thioxo-5,7-diazaspiro[3.4]oct-7-yl]-3-(trifluoromethyl)- Preparation Products And Raw materials
Tag:2-Pyridinecarbonitrile, 5-[5-[4-[(1-methyl-4-piperidinyl)oxy]phenyl]-8-oxo-6-thioxo-5,7-diazaspiro[3.4]oct-7-yl]-3-(trifluoromethyl)-(1332390-06-3) Related Product Information