Acetamide, N-[4-[3-[(4-chlorophenyl)methylene]-2,3-dihydro-2-oxo-5-phenyl-1H-pyrrol-1-yl]phenyl]-

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Acetamide, N-[4-[3-[(4-chlorophenyl)methylene]-2,3-dihydro-2-oxo-5-phenyl-1H-pyrrol-1-yl]phenyl]- manufacturers

  • inS3-54-A26
  • inS3-54-A26 pictures
  • $70.00
  • 2026-08-08
  • CAS:328998-77-2
  • Purity: 99.57%
  • Supply Ability: 10g
Acetamide, N-[4-[3-[(4-chlorophenyl)methylene]-2,3-dihydro-2-oxo-5-phenyl-1H-pyrrol-1-yl]phenyl]- Basic information
Product Name:Acetamide, N-[4-[3-[(4-chlorophenyl)methylene]-2,3-dihydro-2-oxo-5-phenyl-1H-pyrrol-1-yl]phenyl]-
Synonyms:Acetamide, N-[4-[3-[(4-chlorophenyl)methylene]-2,3-dihydro-2-oxo-5-phenyl-1H-pyrrol-1-yl]phenyl]-;inS3-54-A26;inS3 54 A26,inS354A26,inS-3-54-A26;inS3-54-A26, 10 mM in DMSO
CAS:328998-77-2
MF:C25H19ClN2O2
MW:414.88
EINECS:
Product Categories:
Mol File:328998-77-2.mol
Acetamide, N-[4-[3-[(4-chlorophenyl)methylene]-2,3-dihydro-2-oxo-5-phenyl-1H-pyrrol-1-yl]phenyl]- Structure
Acetamide, N-[4-[3-[(4-chlorophenyl)methylene]-2,3-dihydro-2-oxo-5-phenyl-1H-pyrrol-1-yl]phenyl]- Chemical Properties
Boiling point 700.7±60.0 °C(Predicted)
density 1.343±0.06 g/cm3(Predicted)
pka14.56±0.70(Predicted)
Safety Information
MSDS Information
Acetamide, N-[4-[3-[(4-chlorophenyl)methylene]-2,3-dihydro-2-oxo-5-phenyl-1H-pyrrol-1-yl]phenyl]- Usage And Synthesis
DescriptioninS3-54-A26 is a novel inhibitor of the DNA-binding domain (DBD) of STAT3, suppressing tumor growth, metastasis and STAT3 target gene expression in vivo.
UsesinS3-54-A26 is a STAT3 inhibitor. inS3-54-A26 has a toxic IC50 of 4.0 μM for non-cancerous lung fibroblasts[1].
References[1] Huang W, et al. Small-molecule inhibitors targeting the DNA-binding domain of STAT3 suppress tumor growth, metastasis and STAT3 target gene expression in vivo. Oncogene. 2016 Feb 11;35(6):783-92. DOI:10.1038/onc.2015.215
Acetamide, N-[4-[3-[(4-chlorophenyl)methylene]-2,3-dihydro-2-oxo-5-phenyl-1H-pyrrol-1-yl]phenyl]- Preparation Products And Raw materials
Tag:Acetamide, N-[4-[3-[(4-chlorophenyl)methylene]-2,3-dihydro-2-oxo-5-phenyl-1H-pyrrol-1-yl]phenyl]-(328998-77-2) Related Product Information
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