NEUROPEPTIDE S (HUMAN)
| 中文名称 | NEUROPEPTIDE S (HUMAN) |
|---|---|
| 中文同义词 | 神经肽S (人类);L-丝氨酰-L-苯丙氨酰-L-精氨酰-L-天冬氨酰胺酰甘氨酰-L-缬氨酰甘氨酰-L-苏氨酰甘氨酰-L-蛋氨酰-L-赖氨酰-L-赖氨酰-L-苏氨酰-L-丝氨酰-L-苯丙氨酰-L-谷氨酰胺酰-L-精氨酰-L-丙氨酰-L-赖氨酰-L-丝氨酸;内源性神经肽S受体激动剂,人源;神经肽S (人类)、 NEURO PEPTIDE S (HUMAN);NEUROKININ S(HUMAN)|CAS 412938-67-1;受体激动剂多肽Neuropeptide S (human) |
| 英文名称 | NEUROPEPTIDE S (HUMAN) |
| 英文同义词 | SFRNGVGTGMKKTSFQRAKS;SER-PHE-ARG-ASN-GLY-VAL-GLY-THR-GLY-MET-LYS-LYS-THR-SER-PHE-GLN-ARG-ALA-LYS-SER;NPS (HUMAN);NEUROPEPTIDE S (HUMAN);H-SER-PHE-ARG-ASN-GLY-VAL-GLY-THR-GLY-MET-LYS-LYS-THR-SER-PHE-GLN-ARG-ALA-LYS-SER-OH;REF DUPL: H-Ser-Phe-Arg-Asn-Gly-Val-Gly-Ser-Gly-Ala-Lys-Lys-Thr-Ser-Phe-Arg-Arg-Ala-Lys-Gln-OH;Neuropeptide S, NPS, human;Neuropeptide S (huMan) NPS (huMan) |
| CAS号 | 412938-67-1 |
| 分子式 | C93H155N31O28S |
| 分子量 | 2187.48 |
| EINECS号 | |
| 相关类别 | 多肽;标准品;peptide;Various peptides |
| Mol文件 | 412938-67-1.mol |
| 结构式 |  |
NEUROPEPTIDE S (HUMAN) 性质
| 密度 | 1.49±0.1 g/cm3(Predicted) |
|---|---|
| 形态 | 固体 |
| 颜色 | 白色至米白色 |
| 序列 | Ser-Phe-Arg-Asn-Gly-Val-Gly-Thr-Gly-Met-Lys-Lys-Thr-Ser-Phe-Gln-Arg-Ala-Lys-Ser |
EC50: 9.4 nM (neuropeptide S receptor)
Neuropeptide S human (4 pM to 1.7 nM; 48 hours) retains full agonist activity with an EC 50 of 6.7 ± 2.4 nM, the binding of [ 125I ] Y10-hNPS to CHO cells stably expressing hNPSR is saturable with high affinity (K d = 0.33 ± 0.12 nM). Neuropeptide S human (1 pM-3 μM; 48 hours) are used to compete with 0.15 nM [ 125I I] Y10-NPS, [ 125I I] Y10-NPS is displaceable by increasing concentrations of human NPS (IC 50 = 0.42 ± 0.12 nM).
Neuropeptide S human (0.1 nM-1 nM; i.c.v.) causes a significant increase in locomotor activity, the total distance traveled, percentage of time moving, number of rearing events, and center entries are also significantly increased in mice.
| Animal Model: | Male C57Bl/6 mice |
| Dosage: | 0.1 nM, 1 nM |
| Administration: | Intracerebroventricular (i.c.v.) injection |
| Result: | Increased locomotor activity and promoted wakefulness. |
安全信息
| 更新日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
|---|---|---|---|---|---|
| 2026/09/15 | HY-P1389 | Neuropeptide S (human) | 412938-67-1 | 1 mg | 1120元 |
| 2026/09/15 | HY-P1389 | Neuropeptide S (human) | 5 mg | 2800元 |