5,8,11,14-Eicosatetraenamide, N-[(1R)-2-hydroxy-1-methylethyl]-13-methyl-, (5Z,8Z,11Z,13S,14Z)-

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5,8,11,14-Eicosatetraenamide, N-[(1R)-2-hydroxy-1-methylethyl]-13-methyl-, (5Z,8Z,11Z,13S,14Z)- Basic information
Product Name:5,8,11,14-Eicosatetraenamide, N-[(1R)-2-hydroxy-1-methylethyl]-13-methyl-, (5Z,8Z,11Z,13S,14Z)-
Synonyms:AMG-315;5,8,11,14-Eicosatetraenamide, N-[(1R)-2-hydroxy-1-methylethyl]-13-methyl-, (5Z,8Z,11Z,13S,14Z)-
CAS:2244425-65-6
MF:C24H41NO2
MW:375.59
EINECS:
Product Categories:
Mol File:2244425-65-6.mol
5,8,11,14-Eicosatetraenamide, N-[(1R)-2-hydroxy-1-methylethyl]-13-methyl-, (5Z,8Z,11Z,13S,14Z)- Structure
5,8,11,14-Eicosatetraenamide, N-[(1R)-2-hydroxy-1-methylethyl]-13-methyl-, (5Z,8Z,11Z,13S,14Z)- Chemical Properties
Boiling point 536.0±50.0 °C(Predicted)
density 0.931±0.06 g/cm3(Predicted)
pka14.51±0.10(Predicted)
Safety Information
MSDS Information
5,8,11,14-Eicosatetraenamide, N-[(1R)-2-hydroxy-1-methylethyl]-13-methyl-, (5Z,8Z,11Z,13S,14Z)- Usage And Synthesis
DescriptionAMG-315 is a Potent Endocannabinoid Ligand with Stability to Metabolizing Enzymes. AMG-315 is a chiral arachidonoyl ethanolamide (AEA) analogue or (13S,1′R)-dimethylanandamide. AMG-315 is a high affinity ligand for the CB1 receptor (Ki of 7.8 ± 1.4 nM) that behaves as a potent CB1 agonist in vitro (EC50 = 0.6 ± 0.2 nM). AMG-315 is the first potent AEA analogue with significant stability for all endocannabinoid hydrolyzing enzymes as well as the oxidative enzymes COX-2. AMG-315 will serve as a very useful endocannabinoid probe.
5,8,11,14-Eicosatetraenamide, N-[(1R)-2-hydroxy-1-methylethyl]-13-methyl-, (5Z,8Z,11Z,13S,14Z)- Preparation Products And Raw materials
Tag:5,8,11,14-Eicosatetraenamide, N-[(1R)-2-hydroxy-1-methylethyl]-13-methyl-, (5Z,8Z,11Z,13S,14Z)-(2244425-65-6) Related Product Information