CDK12-IN-6

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CDK12-IN-6 Suppliers list
Company Name: BOC Sciences
Tel: 16314854226; +16314854226
Email: inquiry@bocsci.com
Products Intro: Product Name:CDK12-IN-6
CAS:2651196-71-1
Remarks:Please reach out to us for more information about custom solutions.
Company Name: Shanghai Merlot Chemical Co., LTD  
Tel: 15821661757
Email: 226174156@qq.com
Products Intro: Product Name:CDK12-IN-6
CAS:2651196-71-1
Purity:95% Package:1g；5g
Company Name: TargetMol Chemicals Inc.  
Tel: 15002134094
Email: marketing@targetmol.cn
Products Intro: Product Name:CDK12-IN-6
CAS:2651196-71-1
Package:1removed
CDK12-IN-6 Basic information
Product Name:CDK12-IN-6
Synonyms:CDK12-IN-6
CAS:2651196-71-1
MF:C20H21F2N9
MW:425.45
EINECS:
Product Categories:
Mol File:2651196-71-1.mol
CDK12-IN-6 Structure
CDK12-IN-6 Chemical Properties
form Solid
color White to off-white
Safety Information
MSDS Information
CDK12-IN-6 Usage And Synthesis
UsesCDK12-IN-6, a pyrazolotriazine, is a potent CDK12 inhibitor with an IC50 of 1.19 μM at high ATP (2 mM). CDK12-IN-6 has no effect on CDK2/Cyclin E (IC50>20 μM) and CDK9/Cyclin T1 (IC50>20 μM) at high ATP (2 mM) (WO2021116178A1)[1].
IC 50CDK12: 1.19 μM (IC50); CDK2/cyclinE: >20 μM (IC50); CDK9/cyclinT1: >20 μM (IC50)
References[1] Kai Thede, et al. Pyrazolotriazines. WO2021116178A1.
CDK12-IN-6 Preparation Products And Raw materials
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