比地索胺
| 中文名称 | 比地索胺 |
|---|---|
| 中文同义词 | 比地索胺;化合物 T12858;比地索胺,10 MM DMSO 溶液 |
| 英文名称 | Bidisomide |
| 英文同义词 | (R)-α-[2-[Acetyl(isopropyl)amino]ethyl]-α-(2-chlorophenyl)-1-piperidinebutanamide;(αR)-α-[2-(Acetylisopropylamino)ethyl]-α-(2-chlorophenyl)-1-piperidinebutanamide;SC-40230;(S)-α-[2-[Acetyl(isopropyl)amino]ethyl]-α-(2-chlorophenyl)-1-piperidinebutanamide;(αS)-α-[2-(Acetylisopropylamino)ethyl]-α-(2-chlorophenyl)-1-piperidinebutanamide;1-Piperidinebutanamide, alpha-(2-(acetyl(1-methylethyl)amino)ethyl)-alpha-(2-chlorophenyl)-, (+-)-;Bidisomida;Bidisomida [inn-spanish] |
| CAS号 | 116078-65-0 |
| 分子式 | C22H34ClN3O2 |
| 分子量 | 407.97726 |
| EINECS号 | |
| 相关类别 | |
| Mol文件 | 116078-65-0.mol |
| 结构式 |  |
比地索胺 性质
| 熔点 | 140-141° |
|---|---|
| 储存条件 | Store at -20°C |
| 溶解度 | 溶于二甲基亚砜 |
| 形态 | 固体 |
| 颜色 | 米白色至浅黄色 |
The antiarrhythmic effects of Bidisomide, a new class I antiarrhythmic drug is investigated in early-phase ventricular arrhythmias induced by coronary artery occlusion and reperfusion in anesthetized rats. Bidisomide (5 mg/kg) reduces the number of premature ventricular complexes and the incidence of ventricular tachycardia and ventricular fibrillation similarly to Mexiletine (MXT) and Disopyramide (DSP) in rats with ventricular arrhythmias induced by coronary artery occlusion. In rats with ventricular arrhythmias induced by coronary artery reperfusion following a 5 min coronary occlusion, the antiarrhythmic effects of 5 mg/kg of Bidisomide are similar to those of the same doses of MXT and DSP. All three drugs significantly slow the heart rate.
安全信息
| 更新日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
|---|---|---|---|---|---|
| 2025/12/22 | HY-U00232 | 比地索胺 Bidisomide | 116078-65-0 | 1 mg | 1438元 |
| 2025/12/22 | HY-U00232 | 比地索胺 Bidisomide | 116078-65-0 | 5mg | 3563元 |