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| | Aminoguanidine bicarbonate Basic information |
| Product Name: | Aminoguanidine bicarbonate | | Synonyms: | Aminoguanidine bicarbonate ;Aminoguanidine hydrogen carbonate;AMINOGUANIDINE BICARBONATE CRYSTALLINE;1-AMINOGUANIDINIUM HYDROGEN CARBONATE OE;Aminoguanidine bicarbonate, 98.50%;1-AMINOGUANIDINE BICARBONATE;1-AMINOGUANIDINE HYDROGEN CARBONATE;1-AMINOGUANIDINIUM HYDROGEN CARBONATE;GUANYLHYDRAZINE BICARBONATE | | CAS: | 2582-30-1 | | MF: | C2H8N4O3 | | MW: | 136.11 | | EINECS: | 219-956-7 | | Product Categories: | white powder;Pharmaceutical Intermediates;2582-30-1 | | Mol File: | 2582-30-1.mol |  |
| | Aminoguanidine bicarbonate Chemical Properties |
| Melting point | 170-172 °C (dec.)(lit.) | | density | 1,6 g/cm3 | | bulk density | 700kg/m3 | | storage temp. | Store below +30°C. | | solubility | H2O: soluble2.7g/L at 20°C | | pka | 6.19[at 20 ℃] | | form | Crystalline Powder | | color | White to off-white | | PH | 8.9 (5g/l, H2O, 20℃) | | Water Solubility | <5 g/L (20 ºC) | | BRN | 3569869 | | Cosmetics Ingredients Functions | SKIN CONDITIONING | | InChI | InChI=1S/CH6N4.CH2O3/c2-1(3)5-4;2-1(3)4/h4H2,(H4,2,3,5);(H2,2,3,4) | | InChIKey | OTXHZHQQWQTQMW-UHFFFAOYSA-N | | SMILES | N(N)C(=N)N.C(O)(=O)O | | LogP | -6.61 at 25℃ | | CAS DataBase Reference | 2582-30-1(CAS DataBase Reference) | | EPA Substance Registry System | Carbonic acid, compd. with hydrazinecarboximidamide (1:1) (2582-30-1) |
| Hazard Codes | Xi,Xn,N | | Risk Statements | 52/53-43-36/37/38-20/21/22-51/53 | | Safety Statements | 22-24/25-37-24-36-26-36/37 | | RIDADR | UN3077 | | WGK Germany | 2 | | RTECS | FG1772000 | | Autoignition Temperature | 245 °C | | TSCA | TSCA listed | | HazardClass | 9 | | PackingGroup | III | | HS Code | 29280090 | | Storage Class | 13 - Non Combustible Solids | | Hazard Classifications | Aquatic Chronic 2
Skin Sens. 1 | | Toxicity | LD50 orally in Rabbit: > 5000 mg/kg |
| | Aminoguanidine bicarbonate Usage And Synthesis |
| Chemical Properties | White to off-white crystalline powder. It is almost insoluble in water, alcohol and other acids. | | Uses | Aminoguanidine bicarbonate (AGB) is of practical importance because of its use in dyes, dispersants, explosives and other commercial applications. It is used in the synthesis of antitumor agents and antileukemic activity. Also used in the synthesis of neuraminidase inhibitors in the inhibition of influenze. | | Application | Aminoguanidine bicarbonate is an inhibitor of NOS (nitric oxide synthase). Aminoguanidine bicarbonate is used to study the effect of addition of polyamines to rat embryo cell cultures infected with adenovirus type 5. | | Biochem/physiol Actions | Aminoguanidine bicarbonate protects the cells infected with adenovirus from chromosomal damage. Aminoguanidine is a specific and highly effective inhibitor of diamine oxidase present in fetal calf serum. | | Synthesis | A synthesis method of aminoguanidine bicarbonate includes reacting an acidic aqueous hydrazine hydrate solution with calcium cyanamide in an elevated temperature to produce an aminoguanidine solution, recovering the solution, and reacting therewith an alkali metal bicarbonate to produce relatively high purity aminoguanidine bicarbonate. | | storage | +4°C |
| | Aminoguanidine bicarbonate Preparation Products And Raw materials |
| Raw materials | Hydrazinium hydroxide solution-->Ammonium bicarbonate-->2-Methyl-2-thiopseudourea sulfate-->Hydrazine sulfate-->Calcium cyanamide-->Cyanamide-->Calcium oxalate-->Nitroguanidine | | Preparation Products | 7-BROMO-3-TRIFLUOROMETHYL-IMIDAZO[1,2-B][1,2,4]TRIAZINE-->METOSULAM-->3-Amino-1,2,4-Triazole-->Mitoguazone-->AMINOGUANIDINE-->2-(2,3-Dichlorophenyl)-2-guanidinyliminoacetonitrile-->GUANABENZ ACETATE-->5-METHYL-[1,2,4]TRIAZOLO[1,5-C]QUINAZOLIN-2-YLAMINE-->1H-Pyrazole-1-carboximidamide,2,5-dihydro-4-(2-hydroxyethyl)-3-methyl-5-oxo-(9CI)-->2H-Indazole-2-carboximidamide,1,3,4,5,6,7-hexahydro-3-oxo-(9CI)-->OXALYL MONOGUANYLHYDRAZIDE-->4H-Cyclopentapyrimidin-4-one, 2,3-diamino-3,5,6,7-tetrahydro- (9CI) |
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