4-Quinazolinamine, 2-(3-pyridinyl)-N-(2-thienylmethyl)- manufacturers
- PDE5-IN-9
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- $30.00
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2026-07-15
- CAS:157862-84-5
- Purity: 99.98%
- Supply Ability: 10g
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| | 4-Quinazolinamine, 2-(3-pyridinyl)-N-(2-thienylmethyl)- Basic information |
| | 4-Quinazolinamine, 2-(3-pyridinyl)-N-(2-thienylmethyl)- Chemical Properties |
| Boiling point | 447.8±45.0 °C(Predicted) | | density | 1.337±0.06 g/cm3(Predicted) | | pka | 4.68±0.30(Predicted) | | form | Solid | | color | White to off-white |
| | 4-Quinazolinamine, 2-(3-pyridinyl)-N-(2-thienylmethyl)- Usage And Synthesis |
| Uses | PDE5-IN-9 (Compound 59) is a PDE5 inhibitor (IC50: 11.2 μM). PDE5-IN-9 shows interaction with Gln 817, Tyr 612, and Ala 767 amino acid residues. PDE5-IN-9 can be used for research of cardiovascular disease[1]. | | IC 50 | PDE5 | | References | [1] Sarvesh Paliwal, et al. Pharmacophore and molecular docking based identification of novel structurally diverse PDE-5 inhibitors. Medicinal Chemistry Research. 2015, 24, 576-587. |
| | 4-Quinazolinamine, 2-(3-pyridinyl)-N-(2-thienylmethyl)- Preparation Products And Raw materials |
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