2-Piperidinemethanol, 1-[2-[4-[[4-(3,4-dichlorophenyl)-2-thiazolyl]amino]phenyl]ethyl]-4-hydroxy-, (2R,4S)-

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2-Piperidinemethanol, 1-[2-[4-[[4-(3,4-dichlorophenyl)-2-thiazolyl]amino]phenyl]ethyl]-4-hydroxy-, (2R,4S)- Suppliers list
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Products Intro: Product Name:Amgen-23
CAS:1448706-15-7
Purity:98% by HPLC Remarks:Please reach out to us for more information about custom solutions.
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Products Intro: Product Name:Amgen-23
CAS:1448706-15-7
Purity:99% Package:$250.9/5mg;$410.9/10mg;$820.9/25mg;$1300.9/50mg;Bulk package Remarks:99%
Company Name: Wuhan Jingkang en Biomedical Technology Co., Ltd
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Products Intro: Product Name:Amgen-23
CAS:1448706-15-7
Purity:0.98 Package:10G:100G
Company Name: Shanghai Lollane Biological Technology Co.,Ltd.  
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Products Intro: Product Name:Amgen-23
CAS:1448706-15-7
Purity:98% HPLC Package:5mg，10mg，50mg，100mg，1g，5g
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Products Intro: Product Name:Amgen-23
CAS:1448706-15-7
Purity:98 Package:1G,5G,10G,50G,100G,500G
2-Piperidinemethanol, 1-[2-[4-[[4-(3,4-dichlorophenyl)-2-thiazolyl]amino]phenyl]ethyl]-4-hydroxy-, (2R,4S)- Basic information
Product Name:2-Piperidinemethanol, 1-[2-[4-[[4-(3,4-dichlorophenyl)-2-thiazolyl]amino]phenyl]ethyl]-4-hydroxy-, (2R,4S)-
Synonyms:2-Piperidinemethanol, 1-[2-[4-[[4-(3,4-dichlorophenyl)-2-thiazolyl]amino]phenyl]ethyl]-4-hydroxy-, (2R,4S)-;Amgen-23;(2R,4S)-1-[2-(4-{[4-(3,4-dichlorophenyl)-1,3-thiazol-2-yl]amino}phenyl)ethyl]-2-(hydroxymethyl)piperidin-4-ol;(2R,4S)-1-(4-((4-(3,4-Dichlorophenyl)thiazol-2-yl)amino)phenethyl)-2-(hydroxymethyl)piperidin-4-ol
CAS:1448706-15-7
MF:C23H25Cl2N3O2S
MW:478.43
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Mol File:1448706-15-7.mol
2-Piperidinemethanol, 1-[2-[4-[[4-(3,4-dichlorophenyl)-2-thiazolyl]amino]phenyl]ethyl]-4-hydroxy-, (2R,4S)- Structure
2-Piperidinemethanol, 1-[2-[4-[[4-(3,4-dichlorophenyl)-2-thiazolyl]amino]phenyl]ethyl]-4-hydroxy-, (2R,4S)- Chemical Properties
Boiling point 673.6±65.0 °C(Predicted)
density 1.369±0.06 g/cm3(Predicted)
form Solid
pka14.73±0.40(Predicted)
color White to off-white
Safety Information
MSDS Information
2-Piperidinemethanol, 1-[2-[4-[[4-(3,4-dichlorophenyl)-2-thiazolyl]amino]phenyl]ethyl]-4-hydroxy-, (2R,4S)- Usage And Synthesis
UsesAmgen-23 (compound 23) is a potent sphingosine kinases (SPHK) inhibitor with IC50 values of 20 nM and 1.6 μM for SPHK1 and SPHK2, respectively. Amgen-23 can be used for researching anticancer[1].
IC 50SphK1: 20 nM (IC50); SphK2: 1.6 μM (IC50)
References[1] Gustin DJ, et al. Structure guided design of a series of sphingosine kinase (SphK) inhibitors. Bioorg Med Chem Lett. 2013 Aug 15;23(16):4608-16. DOI:10.1016/j.bmcl.2013.06.030
2-Piperidinemethanol, 1-[2-[4-[[4-(3,4-dichlorophenyl)-2-thiazolyl]amino]phenyl]ethyl]-4-hydroxy-, (2R,4S)- Preparation Products And Raw materials
Tag:2-Piperidinemethanol, 1-[2-[4-[[4-(3,4-dichlorophenyl)-2-thiazolyl]amino]phenyl]ethyl]-4-hydroxy-, (2R,4S)-(1448706-15-7) Related Product Information