4,5-dihydroxy-2-oxo-6-phosphonooxy-hexanoic acid

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Products Intro: Product Name:3-Deoxy-2-keto-6-phosphogluconic acid lithium salt
CAS:27244-54-8
Purity:>=95% (TLC) Package:$467.9/10mg;$2381.9/50mg;Bulk package Remarks:95% (TLC)
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Products Intro: Product Name:3-Deoxy-2-keto-6-phospho-D-gluconate lithium salt
CAS:27244-54-8
Purity:94%
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Products Intro: Product Name:3-Deoxy-2-keto-6-phospho-D-gluconate lithium
CAS:27244-54-8
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Products Intro: Product Name:3-Deoxy-2-keto-6-phosphogluconic acid lithium salt
CAS:27244-54-8
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Products Intro: Product Name:3-Deoxy-2-keto-6-phospho-D-gluconate lithium
CAS:27244-54-8
4,5-dihydroxy-2-oxo-6-phosphonooxy-hexanoic acid Basic information
Product Name:4,5-dihydroxy-2-oxo-6-phosphonooxy-hexanoic acid
Synonyms:4,5-dihydroxy-2-oxo-6-phosphonooxy-hexanoic acid;2-Keto-3-deoxy-6-phosphogluconate;2-Keto-2,3-dideoxy-6-O-phosphono-D-gluconic acid;3-Deoxy-D-erythro-2-hexulosonic acid 6-phosphoric acid;KDPG;(4S,5R)-4,5-Dihydroxy-2-oxo-6-phosphonooxyhexanoic acid lithium salt;2-Dehydro-3-deoxy-6-phospho-D-gluconate lithium salt;2-Keto-3-deoxy-6-phosphogluconate lithium salt
CAS:27244-54-8
MF:C6H11O9P
MW:258.12
EINECS:
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Mol File:27244-54-8.mol
4,5-dihydroxy-2-oxo-6-phosphonooxy-hexanoic acid Structure
4,5-dihydroxy-2-oxo-6-phosphonooxy-hexanoic acid Chemical Properties
storage temp. -20°C
form powder
color white
Optical Rotation[α]/D 9.0±1.0°, 3 hr, c = 0.1 in H2O
InChI1S/C6H11O9P/c7-3(1-4(8)6(10)11)5(9)2-15-16(12,13)14/h3,5,7,9H,1-2H2,(H,10,11)(H2,12,13,14)/t3-,5+/m0/s1
InChIKeyOVPRPPOVAXRCED-WVZVXSGGSA-N
SMILES[P](=O)(OC[C@@H](O)[C@@H](O)CC(=O)C(=O)O)(O)O
Safety Information
WGK Germany 3
Storage Class11 - Combustible Solids
MSDS Information
4,5-dihydroxy-2-oxo-6-phosphonooxy-hexanoic acid Usage And Synthesis
DefinitionChEBI: The 5-phospho derivative of 2-dehydro-D-gluconic acid.
Biological Activity2-dehydro-3-deoxy-phosphogluconate is a substrate for the enzyme 2-dehydro-3-deoxy-phosphogluconate aldolase which converts it into D-glyceraldehyde 3-phosphate plus pyruvate. ', 'Metabolite in the pentose phosphate pathway, generating NADPH and pentoses; and in the in pentose and glucuronate interconversions; key intermediate in the Entner-Doudoroff pathway of some bacteria, substrate of 2-Keto-3-deoxy-6-phosphogluconate (KDPG) aldolase, catalyzing the reversible cleavage of KDPG to pyruvate and glyceraldehyde-3-phosphate. It was found to be the carbon catabolite repression signal of phenylacetic acid metabolism in P. putida KT2440. Expression from Pu was repressed mainly via PtsN in response to high levels of 2-dehydro-3-deoxygluconate-6-phosphate.
4,5-dihydroxy-2-oxo-6-phosphonooxy-hexanoic acid Preparation Products And Raw materials
Raw materials4,5,6-trihydroxy-2-oxo-hexanoic acid-->Triose phosphate-->Pyruvic acid
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