Benzenesulfonamide, 4-[2-[2-(ethylthio)-4-oxo-3(4H)-quinazolinyl]ethyl]- manufacturers
- COX-2-IN-18
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- $342.00
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2026-07-14
- CAS:1038061-96-9
- Purity: 98.21%
- Supply Ability: 10g
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| | Benzenesulfonamide, 4-[2-[2-(ethylthio)-4-oxo-3(4H)-quinazolinyl]ethyl]- Basic information |
| | Benzenesulfonamide, 4-[2-[2-(ethylthio)-4-oxo-3(4H)-quinazolinyl]ethyl]- Chemical Properties |
| Boiling point | 621.3±65.0 °C(Predicted) | | density | 1.38±0.1 g/cm3(Predicted) | | pka | 10.15±0.10(Predicted) | | form | Solid | | color | White to off-white |
| | Benzenesulfonamide, 4-[2-[2-(ethylthio)-4-oxo-3(4H)-quinazolinyl]ethyl]- Usage And Synthesis |
| Uses | COX-2-IN-18 (Compound 3) is a potent inhibitor of COX-2. COX-2-IN-18 possesses good COX-2 inhibitory activity (IC50 = 0.775 μM) compared to the reference agent, Celecoxib (IC50 = 0.153 μM). COX-2-IN-18 has the potential for the research of cancer diseases[1]. | | References | [1] El-Azab AS, et al. Antitumor activity, multitarget mechanisms, and molecular docking studies of quinazoline derivatives based on a benzenesulfonamide scaffold: Cell cycle analysis. Bioorg Chem. 2020;104:104345. DOI:10.1016/j.bioorg.2020.104345 |
| | Benzenesulfonamide, 4-[2-[2-(ethylthio)-4-oxo-3(4H)-quinazolinyl]ethyl]- Preparation Products And Raw materials |
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