| Company Name: |
Shanghai YuanYe Biotechnology Co., Ltd.
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| Tel: |
021-61312847; 18021002903 |
| Email: |
3008007409@qq.com |
| Products Intro: |
Product Name:CYP1B1-IN-7
CAS:52601-58-8
Purity:98% Package:5mg Remarks:S35238
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NSC54911 manufacturers
- CYP1B1-IN-7
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- $36.00 / 5mg
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2026-03-13
- CAS:52601-58-8
- Min. Order:
- Purity: 99.49%
- Supply Ability: 10g
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| | NSC54911 Basic information |
| Product Name: | NSC54911 | | Synonyms: | NSC54911;3-(4-Chlorophenyl)-1-(naphthalen-2-yl)prop-2-en-1-one;2-Propen-1-one, 3-(4-chlorophenyl)-1-(2-naphthalenyl)-;CYP1B1-IN-7 | | CAS: | 52601-58-8 | | MF: | C19H13ClO | | MW: | 292.76 | | EINECS: | | | Product Categories: | | | Mol File: | 52601-58-8.mol |  |
| | NSC54911 Chemical Properties |
| Melting point | 162-164 °C(Solv: ethanol (64-17-5)) | | Boiling point | 472.3±37.0 °C(Predicted) | | density | 1.241±0.06 g/cm3(Predicted) | | form | Solid | | color | White to off-white |
| | NSC54911 Usage And Synthesis |
| Uses | CYP1B1-IN-7 (compound 2a) is a selective inhibitor of CYP1B1 (IC50: 75 nM). CYP1B1-IN-7 also reverses resistance (IC50: 29 μM) and exhibits cytotoxicity in the CYP1B1-overexpressing MCF-7 cell line that is resistant to Docetaxel (HY-B0011)[1]. | | References | [1] Raju B, et al. Scaffold hopping for designing of potent and selective CYP1B1 inhibitors to overcome docetaxel resistance: synthesis and evaluation. J Biomol Struct Dyn. 2024 Feb 14:1-19. DOI:10.1080/07391102.2024.2310770 |
| | NSC54911 Preparation Products And Raw materials |
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