Benzamide, 3-[[(16β,17β)-3-(2-bromoethyl)-17-hydroxyestra-1,3,5(10)-trien-16-yl]methyl]- manufacturers
- PBRM
-
- $3230.00
-
2026-04-21
- CAS:1318265-18-7
- Purity: 99.56%
- Supply Ability: 10g
|
| | Benzamide, 3-[[(16β,17β)-3-(2-bromoethyl)-17-hydroxyestra-1,3,5(10)-trien-16-yl]methyl]- Basic information |
| | Benzamide, 3-[[(16β,17β)-3-(2-bromoethyl)-17-hydroxyestra-1,3,5(10)-trien-16-yl]methyl]- Chemical Properties |
| Boiling point | 629.5±55.0 °C(Predicted) | | density | 1.316±0.06 g/cm3(Predicted) | | pka | 14.93±0.60(Predicted) |
| | Benzamide, 3-[[(16β,17β)-3-(2-bromoethyl)-17-hydroxyestra-1,3,5(10)-trien-16-yl]methyl]- Usage And Synthesis |
| Uses | 17β-HSD1-IN-2 (PBRM) is a non-estrogenic and steroidal covalent irreversible inhibitor of 17β-Hydroxysteroid dehydrogenase type 1 (17β-HSD1) (Ki=368 nM). 17β-HSD1-IN-2 can be used for the research of estrogen-dependent disorders[1]. | | References | [1] Trottier A, et al. Insight into the mode of action and selectivity of PBRM, a covalent steroidal inhibitor of 17β-hydroxysteroid dehydrogenase type 1. Biochem Pharmacol. 2017 Nov 15;144:149-161. DOI:10.1016/j.bcp.2017.08.004 |
| | Benzamide, 3-[[(16β,17β)-3-(2-bromoethyl)-17-hydroxyestra-1,3,5(10)-trien-16-yl]methyl]- Preparation Products And Raw materials |
|