2-Pyrimidinamine, 5-fluoro-4-(1-methyl-1H-pyrrolo[2,3-b]pyridin-3-yl)-N-[5-(1-piperazinylmethyl)-2-pyridinyl]-

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2-Pyrimidinamine, 5-fluoro-4-(1-methyl-1H-pyrrolo[2,3-b]pyridin-3-yl)-N-[5-(1-piperazinylmethyl)-2-pyridinyl]- Suppliers list
Company Name: TargetMol Chemicals Inc.
Tel: +17819995354
Email: marketing@targetmol.com
Products Intro: Product Name:CDK4/6-IN-9
CAS:2688098-02-2
Package:100mg;2500USD|25mg;1520USD|50mg;1980USD
Company Name: TargetMol Chemicals Inc.  
Tel: 15002134094
Email: marketing@targetmol.cn
Products Intro: Product Name:CDK4/6-IN-9
CAS:2688098-02-2
Package:100mg/RMB 17500;25mg/RMB 10600;50mg/RMB 13800

2-Pyrimidinamine, 5-fluoro-4-(1-methyl-1H-pyrrolo[2,3-b]pyridin-3-yl)-N-[5-(1-piperazinylmethyl)-2-pyridinyl]- manufacturers

  • CDK4/6-IN-9
  • CDK4/6-IN-9 pictures
  • $2500.00
  • 2026-04-20
  • CAS:2688098-02-2
  • Purity:
  • Supply Ability: 10g
2-Pyrimidinamine, 5-fluoro-4-(1-methyl-1H-pyrrolo[2,3-b]pyridin-3-yl)-N-[5-(1-piperazinylmethyl)-2-pyridinyl]- Basic information
Product Name:2-Pyrimidinamine, 5-fluoro-4-(1-methyl-1H-pyrrolo[2,3-b]pyridin-3-yl)-N-[5-(1-piperazinylmethyl)-2-pyridinyl]-
Synonyms:2-Pyrimidinamine, 5-fluoro-4-(1-methyl-1H-pyrrolo[2,3-b]pyridin-3-yl)-N-[5-(1-piperazinylmethyl)-2-pyridinyl]-;CDK4/6-IN-9
CAS:2688098-02-2
MF:C22H23FN8
MW:418.47
EINECS:
Product Categories:
Mol File:2688098-02-2.mol
2-Pyrimidinamine, 5-fluoro-4-(1-methyl-1H-pyrrolo[2,3-b]pyridin-3-yl)-N-[5-(1-piperazinylmethyl)-2-pyridinyl]- Structure
2-Pyrimidinamine, 5-fluoro-4-(1-methyl-1H-pyrrolo[2,3-b]pyridin-3-yl)-N-[5-(1-piperazinylmethyl)-2-pyridinyl]- Chemical Properties
Boiling point 672.1±65.0 °C(Predicted)
density 1.41±0.1 g/cm3(Predicted)
pka9.02±0.10(Predicted)
Safety Information
MSDS Information
2-Pyrimidinamine, 5-fluoro-4-(1-methyl-1H-pyrrolo[2,3-b]pyridin-3-yl)-N-[5-(1-piperazinylmethyl)-2-pyridinyl]- Usage And Synthesis
UsesCDK4/6-IN-9 (compound 10) is a selective CDK4/6 inhibitor with an IC50 of 905 nM for CDK6/cyclin D1. CDK4/6-IN-9 hasthepotentialformultiple myeloma (MM)research[1].
IC 50CDK6/cyclinD1: 905 nM (IC50); CDK4/cyclinD1
References[1] Kai Yuan, et al. Discovery of novel and orally bioavailable CDK 4/6 inhibitors with high kinome selectivity, low toxicity and long-acting stability for the treatment of multiple myeloma. Eur J Med Chem. 2022 Jan 15;228:114024. DOI:10.1016/j.ejmech.2021.114024
2-Pyrimidinamine, 5-fluoro-4-(1-methyl-1H-pyrrolo[2,3-b]pyridin-3-yl)-N-[5-(1-piperazinylmethyl)-2-pyridinyl]- Preparation Products And Raw materials
Tag:2-Pyrimidinamine, 5-fluoro-4-(1-methyl-1H-pyrrolo[2,3-b]pyridin-3-yl)-N-[5-(1-piperazinylmethyl)-2-pyridinyl]-(2688098-02-2) Related Product Information