4-Phenanthridinamine, 5-ethyl-5,6-dihydro-8,9-dimethoxy- manufacturers
- SARS-CoV-2-IN-16
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- $2500.00
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2026-07-27
- CAS:2761911-40-2
- Purity:
- Supply Ability: 10g
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| | 4-Phenanthridinamine, 5-ethyl-5,6-dihydro-8,9-dimethoxy- Basic information |
| | 4-Phenanthridinamine, 5-ethyl-5,6-dihydro-8,9-dimethoxy- Chemical Properties |
| Boiling point | 473.8±45.0 °C(Predicted) | | density | 1.160±0.06 g/cm3(Predicted) | | pka | 7.05±0.20(Predicted) |
| | 4-Phenanthridinamine, 5-ethyl-5,6-dihydro-8,9-dimethoxy- Usage And Synthesis |
| Uses | SARS-CoV-2-IN-16 (Compound 12) is a potent SARS-CoV-2 nucleocapsid protein (NPro) inhibitor. SARS-CoV-2-IN-16 exhibits potent anti-viral activity with the EC50 of 3.69 μM. SARS-CoV-2-IN-16 binds to NPro with the low KD value of 7.82 μM, suggesting that SARS-CoV-2-IN-16 is a potent NPro ligand[1]. | | References | [1] Yi-Ting Wang, et al. Novel nucleocapsid protein-targeting phenanthridine inhibitors of SARS-CoV-2. Eur J Med Chem. 2022 Jan 5;227:113966. DOI:10.1016/j.ejmech.2021.113966 |
| | 4-Phenanthridinamine, 5-ethyl-5,6-dihydro-8,9-dimethoxy- Preparation Products And Raw materials |
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