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| | CID 90248010 Basic information |
| Product Name: | CID 90248010 | | Synonyms: | CID 90248010;Isopropyl ((((2S,3S,4R,5R)-5-(2-amino-6-ethoxy-9H-purin-9-yl)-2,4-difluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)-L-alaninate;propan-2-yl (2S)-2-[[[(2S,3S,4R,5R)-5-(2-amino-6-ethoxypurin-9-yl)-2,4-difluoro-3-hydroxy-4-methyloxolan-2-yl]methoxy-phenoxyphosphoryl]amino]propanoate | | CAS: | 2481279-61-0 | | MF: | C25H33F2N6O8P | | MW: | 614.54 | | EINECS: | | | Product Categories: | | | Mol File: | 2481279-61-0.mol |  |
| | CID 90248010 Chemical Properties |
| Boiling point | 758.9±70.0 °C(Predicted) | | density | 1.52±0.1 g/cm3(Predicted) | | pka | 11.21±0.70(Predicted) | | form | Solid | | color | White to off-white |
| | CID 90248010 Usage And Synthesis |
| Uses | AL-611 is an HCV NS5B polymerase inhibitor (EC50 = 5 nM). | | References | [1] Wang G, et al. Synthesis and Anti-HCV Activity of Sugar-Modified Guanosine Analogues: Discovery of AL-611 as an HCV NS5B Polymerase Inhibitor for the Treatment of Chronic Hepatitis C. J Med Chem. 2020 Sep 24;63(18):10380-10395. DOI:10.1021/acs.jmedchem.0c00935 |
| | CID 90248010 Preparation Products And Raw materials |
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