RS 79948-197 manufacturers
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| | RS 79948-197 Basic information |
| Product Name: | RS 79948-197 | | Synonyms: | RS 79948-197;(8aR,12aS,13aS)-12-(Ethylsulfonyl)-5,8,8a,9,10,11,12,12a,13,13a-decahydro-3-methoxy-6H-isoquino[2,1-g][1,6]naphthyridine Hydrochloride;(8aR,12aS,13aS)-12-ethylsulfonyl-3-methoxy-5,6,8,8a,9,10,11,12a,13,13a-decahydroisoquinolino[2,1-g][1,6]naphthyridine | | CAS: | 186002-54-0 | | MF: | C19H29ClN2O3S | | MW: | 400.96 | | EINECS: | | | Product Categories: | Chiral Reagents;Intermediates & Fine Chemicals;Pharmaceuticals;Sulfur & Selenium Compounds | | Mol File: | 186002-54-0.mol |  |
| | RS 79948-197 Chemical Properties |
| storage temp. | Store at RT | | form | Powder | | Water Solubility | Soluble to 25 mM in water |
| | RS 79948-197 Usage And Synthesis |
| Uses | .alpha.2A-Adrenoceptor antagonism increases insulin secretion and synergistically augments insulinotropic effect of glibenclamide. | | IC 50 | rat α2A receptor: 0.42 nM (Kd); rat α2B recepter: 0.18 nM (Kd); rat α2C recepter: 0.19 nM (Kd); human α2A-adrenoceptor: 0.6 nM (Kd); human α2B-adrenoceptor: 0.46 nM (Kd); human α2C-adrenoceptor: 0.77 nM (Kd) | | storage | Store at RT |
| | RS 79948-197 Preparation Products And Raw materials |
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