| Company Name: |
TargetMol Chemicals Inc.
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| Tel: |
15002134094 |
| Email: |
marketing@targetmol.cn |
| Products Intro: |
Product Name:β-Glucuronidase/hCAII-IN-1 CAS:2816080-17-6 Package:50mg/RMB 13800;25mg/RMB 10600;100mg/RMB 17500
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| | 4H,5H-Pyrano[3,2-c][1]benzopyran-3-carboxylic acid, 2-amino-8-hydroxy-5-oxo-4-[2-[(2-oxo-2H-1-benzopyran-3-yl)methoxy]phenyl]-, methyl ester Basic information |
| | 4H,5H-Pyrano[3,2-c][1]benzopyran-3-carboxylic acid, 2-amino-8-hydroxy-5-oxo-4-[2-[(2-oxo-2H-1-benzopyran-3-yl)methoxy]phenyl]-, methyl ester Chemical Properties |
| Boiling point | 840.2±65.0 °C(Predicted) | | density | 1.55±0.1 g/cm3(Predicted) | | pka | 8.80±0.70(Predicted) |
| | 4H,5H-Pyrano[3,2-c][1]benzopyran-3-carboxylic acid, 2-amino-8-hydroxy-5-oxo-4-[2-[(2-oxo-2H-1-benzopyran-3-yl)methoxy]phenyl]-, methyl ester Usage And Synthesis |
| Uses | β-Glucuronidase/hCAII-IN-2 (Compound 12e) is a potent β-glucuronidase and hCA II inhibitor with an IC50 of 440.1 μM and 4.91 μM, respectively[1]. | | IC 50 | hCA II: 4.91 μM (IC50); β-glucuronidase: 440.1 μM (IC50) | | References | [1] Arif N, et al. Synthesis, Biological Evaluation, and In Silico Studies of Novel Coumarin-Based 4 H, 5 H-pyrano [3, 2-c] chromenes as Potent β-Glucuronidase and Carbonic Anhydrase Inhibitors. ACS Omega, 2022. |
| | 4H,5H-Pyrano[3,2-c][1]benzopyran-3-carboxylic acid, 2-amino-8-hydroxy-5-oxo-4-[2-[(2-oxo-2H-1-benzopyran-3-yl)methoxy]phenyl]-, methyl ester Preparation Products And Raw materials |
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