|
|
| | 4-Piperidinecarboxamide, N-(4-bromo-3-methylphenyl)-1-[1-[(3-fluorophenyl)methyl]-1H-benzimidazol-2-yl]- Basic information |
| | 4-Piperidinecarboxamide, N-(4-bromo-3-methylphenyl)-1-[1-[(3-fluorophenyl)methyl]-1H-benzimidazol-2-yl]- Chemical Properties |
| density | 1.42±0.1 g/cm3(Predicted) | | form | Solid | | pka | 13.71±0.70(Predicted) | | color | White to off-white |
| | 4-Piperidinecarboxamide, N-(4-bromo-3-methylphenyl)-1-[1-[(3-fluorophenyl)methyl]-1H-benzimidazol-2-yl]- Usage And Synthesis |
| Uses | iPAF1C is a potent inhibitor of polymerase-associated factor 1 complex (PAF1C). iPAF1C has anti-HIV activity[1]. | | References | [1] Shimaa H A Soliman, et al. Enhancing HIV-1 latency reversal through regulating the elongating RNA Pol II pause-release by a small-molecule disruptor of PAF1C. Sci Adv. 2023 Mar 10;9(10):eadf2468. DOI:10.1126/sciadv.adf2468 |
| | 4-Piperidinecarboxamide, N-(4-bromo-3-methylphenyl)-1-[1-[(3-fluorophenyl)methyl]-1H-benzimidazol-2-yl]- Preparation Products And Raw materials |
|