| Company Name: |
Shanghai Yifei Biotechnology Co. , Ltd.
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| Tel: |
021-65675885 18964387627 |
| Email: |
customer_service@efebio.com |
| Products Intro: |
Product Name:HIF-2α agonist 2
CAS:2750141-15-0
Purity:98% Package:1mg;5mg;10mg
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| Company Name: |
TargetMol Chemicals Inc.
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| Tel: |
15002134094 |
| Email: |
marketing@targetmol.cn |
| Products Intro: |
Product Name:HIF-2α agonist 2
CAS:2750141-15-0
Purity:98.87% Package:1mg/RMB 313;5mg/RMB 732;10mg/RMB 1180
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| | 1,2-Benzisothiazol-3-amine, N-(3,5-dibromophenyl)-, 1,1-dioxide Basic information |
| Product Name: | 1,2-Benzisothiazol-3-amine, N-(3,5-dibromophenyl)-, 1,1-dioxide | | Synonyms: | 1,2-Benzisothiazol-3-amine, N-(3,5-dibromophenyl)-, 1,1-dioxide;HIF-2α agonist 2 | | CAS: | 2750141-15-0 | | MF: | C13H8Br2N2O2S | | MW: | 416.09 | | EINECS: | | | Product Categories: | | | Mol File: | 2750141-15-0.mol |  |
| | 1,2-Benzisothiazol-3-amine, N-(3,5-dibromophenyl)-, 1,1-dioxide Chemical Properties |
| Boiling point | 520.3±60.0 °C(Predicted) | | density | 1.96±0.1 g/cm3(Predicted) | | form | Solid | | pka | -2.04±0.20(Predicted) | | color | White to off-white |
| | 1,2-Benzisothiazol-3-amine, N-(3,5-dibromophenyl)-, 1,1-dioxide Usage And Synthesis |
| Uses | HIF-2α agonist 2 (compound 10) is a HIF-2α agonist with an EC50 value of 1.68 μM at the dose of 20 μM. HIF-2α agonist 2 is non-cytotoxic against 786-O-HRE-Luc cells. HIF-2α agonist 2 can be used for oxygen metabolism research[1]. | | References | [1] Yu Y, et al. Insight into the binding mode of HIF-2 agonists through molecular dynamic simulations and biological validation. Eur J Med Chem. 2021 Feb 5;211:112999. DOI:10.1016/j.ejmech.2020.112999 |
| | 1,2-Benzisothiazol-3-amine, N-(3,5-dibromophenyl)-, 1,1-dioxide Preparation Products And Raw materials |
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