Boronic acid, B-[(1R)-3-methyl-1-[[(2R)-1-oxo-2-[(2-pyrazinylcarbonyl)amino]hexyl]amino]butyl]- manufacturers
- LONP1-IN-2
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- $626.00
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2026-07-29
- CAS:2729981-17-1
- Purity: 99.61%
- Supply Ability: 10g
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| | Boronic acid, B-[(1R)-3-methyl-1-[[(2R)-1-oxo-2-[(2-pyrazinylcarbonyl)amino]hexyl]amino]butyl]- Basic information |
| | Boronic acid, B-[(1R)-3-methyl-1-[[(2R)-1-oxo-2-[(2-pyrazinylcarbonyl)amino]hexyl]amino]butyl]- Chemical Properties |
| density | 1.147±0.06 g/cm3(Predicted) | | pka | 9.66±0.43(Predicted) | | form | Solid | | color | White to off-white |
| | Boronic acid, B-[(1R)-3-methyl-1-[[(2R)-1-oxo-2-[(2-pyrazinylcarbonyl)amino]hexyl]amino]butyl]- Usage And Synthesis |
| Uses | LONP1-IN-2 (compound 9e) is a potent and selective LONP1 inhibitor with IC50 values of 0.093 μM and >10 μM for LONP1 and 20S proteasome, respectively. LONP1-IN-2 can be used in research of cancer[1]. | | References | [1] Kingsley LJ, et, al. Structure-Based Design of Selective LONP1 Inhibitors for Probing In Vitro Biology. J Med Chem. 2021 Apr 22;64(8):4857-4869. DOI:10.1021/acs.jmedchem.0c02152 |
| | Boronic acid, B-[(1R)-3-methyl-1-[[(2R)-1-oxo-2-[(2-pyrazinylcarbonyl)amino]hexyl]amino]butyl]- Preparation Products And Raw materials |
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