| Company Name: |
TargetMol |
| Tel: |
400-821-0310 15002144251 |
| Email: |
xuexiang.shao@tsbiochem.com |
|
| | HER2-IN-12 Basic information |
| Product Name: | HER2-IN-12 | | Synonyms: | HER2-IN-12;Imidazo[2,1-b]thiazole-3-carboxylic acid, 5-(4-bromophenyl)-6-(4-morpholinylmethyl)-, hydrazide | | CAS: | 2820126-51-8 | | MF: | C17H18BrN5O2S | | MW: | 436.33 | | EINECS: | | | Product Categories: | | | Mol File: | 2820126-51-8.mol |  |
| | HER2-IN-12 Chemical Properties |
| density | 1.740±0.14 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) | | pka | 10.192±0.20(predicted) |
| | HER2-IN-12 Usage And Synthesis |
| Uses | HER2-IN-12 is a HER2 inhibitor (IC50: 121 nM). HER2-IN-12 can be used in the research of cancers, such as breast cancer[1]. | | IC 50 | HER2: 121 nM (IC50) | | References | [1] Mohamed A Sabry, et al. New thiazole-based derivatives as EGFR/HER2 and DHFR inhibitors: Synthesis, molecular modeling simulations and anticancer activity. Eur J Med Chem. 2022 Aug 10;241:114661. DOI:10.1016/j.ejmech.2022.114661 |
| | HER2-IN-12 Preparation Products And Raw materials |
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