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BOC Sciences |
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| | ONO 3708 Basic information |
| Product Name: | ONO 3708 | | Synonyms: | ONO 3708;(Z)-7-[(1S,5R)-3β-[[(R)-Cyclopentyl(hydroxy)acetyl]amino]-6,6-dimethylbicyclo[3.1.1]hept-2α-yl]-5-heptenoic acid;(Z)-7-[(1S,5R)-3β-[[(R)-Cyclopentylhydroxyacetyl]amino]-6,6-dimethylbicyclo[3.1.1]heptan-2α-yl]-5-heptenoic acid;5-Heptenoic acid, 7-[(1S,2S,3S,5R)-3-[[(2R)-2-cyclopentyl-2-hydroxyacetyl]amino]-6,6-dimethylbicyclo[3.1.1]hept-2-yl]-, (5Z)- | | CAS: | 102191-05-9 | | MF: | C23H37NO4 | | MW: | 391.54 | | EINECS: | | | Product Categories: | | | Mol File: | 102191-05-9.mol |  |
| | ONO 3708 Chemical Properties |
| Boiling point | 598.7±33.0 °C(Predicted) | | density | 1.14±0.1 g/cm3(Predicted) | | pka | 4.76±0.10(Predicted) |
| | ONO 3708 Usage And Synthesis |
| Uses | ONO 3708 is a TXA2/PGH2 receptor antagonist that can inhibit the binding properties of U46619 in unactivated intact human platelets, with an IC50 value of 38 nM[1]. | | References | [1] Kattelman EJ, et al. Characterization of U46619 binding in unactivated, intact human platelets and determination of binding site affinities of four TXA2/PGH2 receptor antagonists (13-APA, BM 13.177, ONO 3708 and SQ 29,548). Thromb Res. 1986 Feb 15;41(4):471-81. DOI:10.1016/0049-3848(86)91692-0 |
| | ONO 3708 Preparation Products And Raw materials |
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