2-[2-(4-Bromophenyl)-1H-benzimidazol-6-yl]-2,3-dihydro-5-(4-morpholinyl)-1H-isoindol-1-one

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2-[2-(4-Bromophenyl)-1H-benzimidazol-6-yl]-2,3-dihydro-5-(4-morpholinyl)-1H-isoindol-1-one Basic information
Product Name:2-[2-(4-Bromophenyl)-1H-benzimidazol-6-yl]-2,3-dihydro-5-(4-morpholinyl)-1H-isoindol-1-one
Synonyms:2-[2-(4-Bromophenyl)-1H-benzimidazol-6-yl]-2,3-dihydro-5-(4-morpholinyl)-1H-isoindol-1-one;CDK-IN-11;T 112
CAS:2376876-87-6
MF:C25H21BrN4O2
MW:489.36
EINECS:
Product Categories:
Mol File:2376876-87-6.mol
2-[2-(4-Bromophenyl)-1H-benzimidazol-6-yl]-2,3-dihydro-5-(4-morpholinyl)-1H-isoindol-1-one Structure
2-[2-(4-Bromophenyl)-1H-benzimidazol-6-yl]-2,3-dihydro-5-(4-morpholinyl)-1H-isoindol-1-one Chemical Properties
Boiling point 754.2±70.0 °C(Predicted)
density 1.525±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(Predicted)
solubility Soluble to 10 mM in DMSO
pka10.31±0.10(Predicted)
Safety Information
MSDS Information
2-[2-(4-Bromophenyl)-1H-benzimidazol-6-yl]-2,3-dihydro-5-(4-morpholinyl)-1H-isoindol-1-one Usage And Synthesis
UsesCDK-IN-11 is a heterocyclic compound that has an action of promoting cardiomyocyte maturation[1].
Biological ActivityT 112 is an estrogen-related receptor gamma (ERRγ) agonist. Promotes maturation of hiPSC-derived cardiomyocytes. T 112 accelerates metabolic and sarcomere maturation in cardiomyocytes, as well as maturation of contractile and electrophysiological properties and ultrastructure organization, when used alone or in combination with other small molecules.
storageStore at -20°C
References[1] Yoshida S, et al. Heterocyclic compound. Japan, JPWO2019189553A1. 2021-03-25.
2-[2-(4-Bromophenyl)-1H-benzimidazol-6-yl]-2,3-dihydro-5-(4-morpholinyl)-1H-isoindol-1-one Preparation Products And Raw materials
Tag:2-[2-(4-Bromophenyl)-1H-benzimidazol-6-yl]-2,3-dihydro-5-(4-morpholinyl)-1H-isoindol-1-one(2376876-87-6) Related Product Information
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