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| | Pyridine, 3-[2-[(4-chloro-1-naphthalenyl)oxy]ethyl]-, 1-oxide Basic information |
| | Pyridine, 3-[2-[(4-chloro-1-naphthalenyl)oxy]ethyl]-, 1-oxide Chemical Properties |
| Melting point | 93-94 °C | | Boiling point | 556.9±35.0 °C(Predicted) | | density | 1.22±0.1 g/cm3(Temp: 20 °C; Press: 760 Torr)(Predicted) | | pka | 0.79±0.10(Predicted) | | form | Solid | | color | White to off-white |
| | Pyridine, 3-[2-[(4-chloro-1-naphthalenyl)oxy]ethyl]-, 1-oxide Usage And Synthesis |
| Uses | DL-175 (compound 13) is a selective GPR84 agonist with biased agonistic activity. DL-175 can selectively activate functional responses in immune cells and induce enhanced chemotaxis and phagocytosis of human bone marrow cells. DL-175 is a potential chemical probe[1]. | | References | [1] Lucy D, et al. A Biased Agonist at Immunometabolic Receptor GPR84 Causes Distinct Functional Effects in Macrophages. ACS Chem Biol. 2019 Sep 20;14(9):2055-2064. DOI:10.1021/acschembio.9b00533 |
| | Pyridine, 3-[2-[(4-chloro-1-naphthalenyl)oxy]ethyl]-, 1-oxide Preparation Products And Raw materials |
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