|
|
| | WAY-652291 Basic information |
| Product Name: | WAY-652291 | | Synonyms: | WAY-652291;1,3-Dimethyl-5-(p-tolyl)-5,9-dihydrofuro[3',4':5,6]pyrido[2,3-d]pyrimidine-2,4,6(1H,3H,8H)-trione;1,3-dimethyl-5-(p-tolyl)-8,9-dihydrofuro[3',4':5,6]pyrido[2,3-d]pyrimidine-2,4,6(1H,3H,5H)-trione;BETbromodomaininhibitor3;Furo[3′,4′:5,6]pyrido[2,3-d]pyrimidine-2,4,6(1H,3H,8H)-trione, 5,9-dihydro-1,3-dimethyl-5-(4-methylphenyl)- | | CAS: | 854137-39-6 | | MF: | C18H17N3O4 | | MW: | 339.35 | | EINECS: | | | Product Categories: | | | Mol File: | 854137-39-6.mol |  |
| | WAY-652291 Chemical Properties |
| Melting point | 294-296 °C (decomp) | | Boiling point | 570.664±60.00 °C(Press: 760.00 Torr)(predicted) | | density | 1.450±0.10 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) | | pka | 1.351±0.40(predicted) | | form | Solid | | color | White to off-white |
| | WAY-652291 Usage And Synthesis |
| Uses | BET bromodomain inhibitor 3 is BET bromodomain inhibitor. BET bromodomain inhibitor 3 has inhibitory effect against BrdT with Ki value of > 40 μM. BET bromodomain inhibitor 3 can be used for the research of contraception, cancer, and heart disease[1]. | | References | [1] Ayoub AM, et al. BET Bromodomain Inhibitors with One-Step Synthesis Discovered from Virtual Screen [published correction appears in J Med Chem. 2017 Jul 27;60(14):6458]. J Med Chem. 2017;60(12):4805-4817. DOI:10.1021/acs.jmedchem.6b01336 |
| | WAY-652291 Preparation Products And Raw materials |
|