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Cato Research Chemicals Inc.
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020-81215950 4000-868-328 |
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customer@uwalab.com |
Products Intro: |
Product Name:2-phenyl-1,2-benzothiazol-3-one CAS:2527-03-9 Purity:95%(HPLC) Package:10mg;25mg;50mg;100mg
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| 2-phenyl-1,2-benzisothiazol-3-(2H)-one Basic information |
Product Name: | 2-phenyl-1,2-benzisothiazol-3-(2H)-one | Synonyms: | 2-phenyl-1,2-benzisothiazol-3-(2H)-one;2-phenylbenzo[d]isothiazol-3(2H)-one;2-phenyl-1,2-benzothiazol-3-one;2-Phenyl-1-thia-2-azaindan-3-one;2-Phenyl-2,3-dihydro-1,2-benzoisothiazole-3-one;PZ-25;RP-62373;1,2-Benzisothiazol-3(2H)-one, 2-phenyl- | CAS: | 2527-03-9 | MF: | C13H9NOS | MW: | 227.28 | EINECS: | | Product Categories: | | Mol File: | 2527-03-9.mol |  |
| 2-phenyl-1,2-benzisothiazol-3-(2H)-one Chemical Properties |
Melting point | 139-140 °C(Solv: ethanol (64-17-5)) | Boiling point | 388.9±25.0 °C(Predicted) | density | 1.338±0.06 g/cm3(Predicted) | pka | -0.55±0.20(Predicted) |
| 2-phenyl-1,2-benzisothiazol-3-(2H)-one Usage And Synthesis |
Uses | Ebsulfur is a benzisothiazolone cytocidal inhibitor targeting the trypanothione reductase (TryR) of Trypanosoma brucei, with IC50 values of 61-293 nM for Trypanosoma brucei. Ebsulfur can be used for the research of African trypanosomiasis[1]. | References | [1] Lu J, et al. Ebsulfur is a benzisothiazolone cytocidal inhibitor targeting the trypanothione reductase of Trypanosoma brucei. J Biol Chem. 2013 Sep 20;288(38):27456-27468. DOI:10.1074/jbc.M113.495101 |
| 2-phenyl-1,2-benzisothiazol-3-(2H)-one Preparation Products And Raw materials |
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