2-phenyl-1,2-benzisothiazol-3-(2H)-one

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Products Intro: Product Name:2-PHENYL-1,2-BENZISOTHIAZOL-3-(2H)-ONE
Purity:0 Package:1g; 5g; 25g; 1kg; 5kg; 25kg Remarks:0
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Products Intro: Product Name:2-Phenyl-1,2-benzisothiazol-3-(2H)-one
CAS:2527-03-9
Purity:0.97 Package:mgs,gs,kgs Remarks:A905492
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Products Intro: Product Name:2-phenylbenzo[d]isothiazol-3(2H)-one
CAS:2527-03-9
Purity:98%
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Products Intro: Product Name:2-phenylbenzo[d]isothiazol-3(2H)-one
CAS:2527-03-9
Purity:99% HPLC Package:25g;100g;1000g;25kg
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Products Intro: Product Name:2-phenyl-1,2-benzothiazol-3-one
CAS:2527-03-9
Purity:95%(HPLC) Package:10mg;25mg;50mg;100mg
2-phenyl-1,2-benzisothiazol-3-(2H)-one Basic information
Product Name:2-phenyl-1,2-benzisothiazol-3-(2H)-one
Synonyms:2-phenyl-1,2-benzisothiazol-3-(2H)-one;2-phenylbenzo[d]isothiazol-3(2H)-one;2-phenyl-1,2-benzothiazol-3-one;2-Phenyl-1-thia-2-azaindan-3-one;2-Phenyl-2,3-dihydro-1,2-benzoisothiazole-3-one;PZ-25;RP-62373;1,2-Benzisothiazol-3(2H)-one, 2-phenyl-
CAS:2527-03-9
MF:C13H9NOS
MW:227.28
EINECS:
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Mol File:2527-03-9.mol
2-phenyl-1,2-benzisothiazol-3-(2H)-one Structure
2-phenyl-1,2-benzisothiazol-3-(2H)-one Chemical Properties
Melting point 139-140 °C(Solv: ethanol (64-17-5))
Boiling point 388.9±25.0 °C(Predicted)
density 1.338±0.06 g/cm3(Predicted)
pka-0.55±0.20(Predicted)
Safety Information
MSDS Information
2-phenyl-1,2-benzisothiazol-3-(2H)-one Usage And Synthesis
UsesEbsulfur is a benzisothiazolone cytocidal inhibitor targeting the trypanothione reductase (TryR) of Trypanosoma brucei, with IC50 values of 61-293 nM for Trypanosoma brucei. Ebsulfur can be used for the research of African trypanosomiasis[1].
References[1] Lu J, et al. Ebsulfur is a benzisothiazolone cytocidal inhibitor targeting the trypanothione reductase of Trypanosoma brucei. J Biol Chem. 2013 Sep 20;288(38):27456-27468. DOI:10.1074/jbc.M113.495101
2-phenyl-1,2-benzisothiazol-3-(2H)-one Preparation Products And Raw materials
Tag:2-phenyl-1,2-benzisothiazol-3-(2H)-one(2527-03-9) Related Product Information

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