Nur77 modulator 3

Nur77 modulator 3 Suppliers list
Company Name: Shanghai Beckham Medical Technology Co., Ltd  
Tel: 13816613772
Email: huahero21@sina.com
Company Name: Shanghai Chaolan Chemical Technology Center  
Tel: QQ:65489617 13301690235
Email: Sales@ATKchemical.com
Company Name: TargetMol Chemicals Inc.  
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Email: marketing@targetmol.cn
Company Name: Shaoguan Qicheng Biotechnology Co., Ltd  
Tel: 18122215013
Email: 780229652@qq.com
Company Name: ATK CHEMICAL COMPANY LIMITED  
Tel: +undefined-21-51877795
Email: ivan@atkchemical.com
Nur77 modulator 3 Basic information
Product Name:Nur77 modulator 3
Synonyms:Nur77 modulator 3;Hydrazinecarbothioamide, 2-(1H-indol-3-ylmethylene)-N-(4-methylphenyl)-, (2E)-
CAS:2097787-75-0
MF:C17H16N4S
MW:308.4
EINECS:
Product Categories:
Mol File:2097787-75-0.mol
Nur77 modulator 3 Structure
Nur77 modulator 3 Chemical Properties
Melting point 195-197 °C
Boiling point 510.286±52.00 °C(Press: 760.00 Torr)(predicted)
density 1.247±0.14 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
pka10.891±0.70(predicted)
form Solid
color White to off-white
Safety Information
MSDS Information
Nur77 modulator 3 Usage And Synthesis
UsesNur77 modulator 3 (9e) can bind to Nur77 and inhibit TGF-β1-induced α-SMA and COLA1 expression in a Nur77-dependent manner. Nur77 modulator 3 induces Nur77 expression and enhances autophagic flux by inhibiting the mTORC1 signaling pathway in vitro and in vivo. Nur77 modulator 3 blocks the progression of hepatic fibrosis[1].
References[1] Lin G, et al. Identification of (E)-1-((1H-indol-3-yl)methylene)-4-substitute-thiosemicarbazones as potential anti-hepatic fibrosis agents. Bioorg Chem. 2023 Dec 16;143:107022. DOI:10.1016/j.bioorg.2023.107022
Nur77 modulator 3 Preparation Products And Raw materials
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