| Company Name: |
Daicel Chiral Technologies (China)CO.,LTD
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| Tel: |
021-50460086-9 15921403865 |
| Email: |
han_yajun@dctc.daicel.com |
| Products Intro: |
Product Name:11-[[2-(2,6-Dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]undecanoic Acid
CAS:2379870-45-6
Purity:95% Package:250MG;1G Remarks:209719
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| | Thalidomide-4-O-C10-COOH Basic information |
| Product Name: | Thalidomide-4-O-C10-COOH | | Synonyms: | Thalidomide-4-O-C10-COOH;11-[[2-(2,6-Dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]undecanoic Acid;Undecanoic acid, 11-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]- | | CAS: | 2379870-45-6 | | MF: | C24H30N2O7 | | MW: | 458.51 | | EINECS: | | | Product Categories: | | | Mol File: | 2379870-45-6.mol |  |
| | Thalidomide-4-O-C10-COOH Chemical Properties |
| Boiling point | 704.561±55.00 °C(Press: 760.00 Torr)(predicted) | | density | 1.290±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) | | form | Solid | | pka | 4.779±0.10(predicted) | | color | White to off-white |
| | Thalidomide-4-O-C10-COOH Usage And Synthesis |
| Uses | Thalidomide-4-O-C10-COOH is a E3 ligase ligand-linker conjugate that can be used in the synthesis of PROTACs. | | IC 50 | Cereblon | | References | [1] Powell CE, et al. Selective degradation-inducing probes for studying cereblon (CRBN) biology. RSC Med Chem. 2021 Jul 6;12(8):1381-1390. DOI:10.1039/d0md00382d |
| | Thalidomide-4-O-C10-COOH Preparation Products And Raw materials |
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