VEGFR-IN-4

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VEGFR-IN-4 Suppliers list
Company Name: Shanghai Beckham Medical Technology Co., Ltd  
Tel: 13816613772
Email: huahero21@sina.com
Company Name: TargetMol Chemicals Inc.  
Tel: 15002134094
Email: marketing@targetmol.cn
VEGFR-IN-4 Basic information
Product Name:VEGFR-IN-4
Synonyms:VEGFR-IN-4;2-Thiophenecarboxamide, 3-[[5-chloro-2-[[4-(4-morpholinyl)phenyl]amino]-4-pyrimidinyl]amino]-N-hydroxy-
CAS:3000483-29-1
MF:C19H19ClN6O3S
MW:446.91
EINECS:
Product Categories:
Mol File:3000483-29-1.mol
VEGFR-IN-4 Structure
VEGFR-IN-4 Chemical Properties
density 1.520±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
pka8.493±0.50(predicted)
Safety Information
MSDS Information
VEGFR-IN-4 Usage And Synthesis
UsesVEGFR-IN-4 (Compound 6e) is an epidermal growth factor receptor (EGFR) inhibitor. VEGFR-IN-4 has potent antiproliferative activity with an IC50 value of 24.6nM against HCC827 cells[1].
References[1] Zuo Y, et al. Design, synthesis and antitumor activity of 4-arylamine substituted pyrimidine derivatives as noncovalent EGFR inhibitors overcoming C797S mutation. Eur J Med Chem. 2023 Dec 29;265:116106. DOI:10.1016/j.ejmech.2023.116106
VEGFR-IN-4 Preparation Products And Raw materials
Tag:VEGFR-IN-4(3000483-29-1) Related Product Information
EGFR Protein, HUMAN (621A.A, HEK293, FC) EGFR protein, HUMAN (BIOTINYLATED, HEK293, HIS-AVI) HER2/CD340 protein, HUMAN (BIOTINYLATED, HEK293, HIS) HER3 Protein, HUMAN (BIOTINYLATED, HEK293, HIS-AVI) AZD-9291 Zanidatamab