|
|
| | Angustine Basic information |
| Product Name: | Angustine | | Synonyms: | Angustine;1-Vinyl-8,13-dihydroindolo[2',3':3,4]pyrido[1,2-b][2,7]naphthyridin-5(7H)-one;Indolo[2',3':3,4]pyrido[1,2-b][2,7]naphthyridin-5(7H)-one, 1-ethenyl-8,13-dihydro- | | CAS: | 40041-96-1 | | MF: | C20H15N3O | | MW: | 313.35 | | EINECS: | | | Product Categories: | | | Mol File: | 40041-96-1.mol |  |
| | Angustine Chemical Properties |
| Melting point | >350 °C(Solv: dichloromethane (75-09-2); methanol (67-56-1)) | | Boiling point | 648.2±55.0 °C(Predicted) | | density | 1.40±0.1 g/cm3(Predicted) | | pka | 16.57±0.20(Predicted) |
| | Angustine Usage And Synthesis |
| Description | A synthesis of angustine has recently been reported. Ethyl oxalate is condensed
with 4-methyl-5-vinylinicotinonitrile followed by condensation of the lactone
thus produced with tryptamine. Hydrolysis and then cyclization of the product
yields angustine. | | Definition | ChEBI: Angustine is a member of beta-carbolines. | | References | Kametani et ai., Heterocycles, 3, (8) 627 (1975) |
| | Angustine Preparation Products And Raw materials |
|