Dimethyl-SGD-1882

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Dimethyl-SGD-1882 Suppliers list
Company Name: TargetMol Chemicals Inc.  
Tel: 15002134094
Email: marketing@targetmol.cn
Dimethyl-SGD-1882 Basic information
Product Name:Dimethyl-SGD-1882
Synonyms:Dimethyl-SGD-1882
CAS:3026416-27-0
MF:C44H43N5O7
MW:753.84
EINECS:
Product Categories:
Mol File:3026416-27-0.mol
Dimethyl-SGD-1882 Structure
Dimethyl-SGD-1882 Chemical Properties
Boiling point 963.815±65.00 °C(Press: 760.00 Torr)(predicted)
density 1.318±0.14 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
pka5.069±0.10(predicted)
Safety Information
MSDS Information
Dimethyl-SGD-1882 Usage And Synthesis
UsesDimethyl-SGD-1882 (Dimethyl-PBD dimer) is a highly potent DNA alkylator, and is used as an antibody-drug conjugate (ADC) cytotoxin. PBD Dimer is a DNA alkylator which inhibits DNA replication[1].
IC 50Pyrrolobenzodiazepines
References[1] Mantaj J, et al. From Anthramycin to Pyrrolobenzodiazepine (PBD)-Containing Antibody-Drug Conjugates (ADCs). Angew Chem Int Ed Engl. 2017 Jan 9;56(2):462-488. DOI:10.1002/anie.201510610
Dimethyl-SGD-1882 Preparation Products And Raw materials
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