| Company Name: |
TargetMol Chemicals Inc.
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| Tel: |
15002134094 |
| Email: |
marketing@targetmol.cn |
| Products Intro: |
Product Name:GSI-18
CAS:362653-62-1
Package:50mg/RMB 13800
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| Product Name: | GSI-18 | | Synonyms: | GSI-18;2-Thiophenesulfonamide, N-[(6R,9S)-5,6,7,8,9,10-hexahydro-6,9-methanobenzocycloocten-11-yl]-, rel- | | CAS: | 362653-62-1 | | MF: | C17H19NO2S2 | | MW: | 333.47 | | EINECS: | | | Product Categories: | | | Mol File: | 362653-62-1.mol |  |
| | GSI-18 Chemical Properties |
| Boiling point | 505.985±60.00 °C(Press: 760.00 Torr)(predicted) | | density | 1.356±0.10 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) | | pka | 10.610±0.20(predicted) |
| | GSI-18 Usage And Synthesis |
| Uses | GSI-18 is a γ-secretase inhibitor with anticancer activity. GSI-18 inhibits the attachment-free growth of pancreatic cancer cells by inhibiting Notch signaling[1]. | | References | [1] Mullendore, et al. "Ligand-dependent Notch signaling is involved in tumor initiation and tumor maintenance in pancreatic cancer." Clinical Cancer Research 15.7 (2009): 2291-2301. DOI:10.1158/1078-0432.CCR-08-2004 |
| | GSI-18 Preparation Products And Raw materials |
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