- 4-Fluoro-2-methoxyaniline
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- $8.00 / 1KG
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2025-09-25
- CAS:450-91-9
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: g-kg-tons, free sample is available
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| Product Name: | 4-FLUORO-2-METHOXYANILINE | | Synonyms: | 2-Methoxy-4-fluoroaniline;4-FLUORO-2-METHOXYANILINE;4-Fluoro-2-MethoxybenzenaMine;o-Anisidine, 4-fluoro-;4-Fluoro-2-methoxy-phenylamine;4-Fluoro-o-anisidine, 2-Amino-5-fluoroanisole;2-AMino-5-fluoroanisole[4-Fluoro-2-Methoxyaniline];2-Amino-5-fluoroanisole | | CAS: | 450-91-9 | | MF: | C7H8FNO | | MW: | 141.14 | | EINECS: | 814-457-6 | | Product Categories: | API | | Mol File: | 450-91-9.mol |  |
| | 4-FLUORO-2-METHOXYANILINE Chemical Properties |
| Boiling point | 215℃ (756 Torr) | | density | 1.176±0.06 g/cm3 (20 ºC 760 Torr) | | refractive index | 1.5400 to 1.5440 | | Fp | 79.5±21.8℃ | | storage temp. | Keep in dark place,Inert atmosphere,Room temperature | | pka | 4.60±0.10(Predicted) | | form | Solid | | color | Colorless to Brown | | InChI | InChI=1S/C7H8FNO/c1-10-7-4-5(8)2-3-6(7)9/h2-4H,9H2,1H3 | | InChIKey | BNRRMRUVYDETQC-UHFFFAOYSA-N | | SMILES | C1(N)=CC=C(F)C=C1OC |
| RIDADR | 2810 | | HazardClass | 6.1 | | PackingGroup | Ⅲ | | HS Code | 2921420090 |
| | 4-FLUORO-2-METHOXYANILINE Usage And Synthesis |
| Physical Form | Yellow to Orange to Brown Solid or liquid | | Application | 4-Fluoro-2-methoxyaniline is a useful synthetic intermediate. It is used to prepare ortho-substituted phenylureas as 5-Hydroxytryptamine (5-HT3) receptor antagonists. It is also used to synthesize hydroxamic acids and their prodrugs as inhibitors for Botulinum neurotoxin A light chain. | | Synthesis | Using 4-fluoro-2-o-methoxynitrobenzene as the starting material, the target compound 4-fluoro-2-methoxyaniline was prepared by hydrogenation reduction reaction.
 | | References | [1] Patent: US6352993, 2002, B1. Location in patent: Page column 30
[2] Patent: CN106366072, 2017, A. Location in patent: Paragraph 0062; 0063; 0064; 0090; 0091; 0092
[3] Patent: CN106366022, 2017, A. Location in patent: Paragraph 0051; 0052; 0056
[4] Patent: US2011/130415, 2011, A1. Location in patent: Page/Page column 102
[5] Patent: WO2018/207120, 2018, A1. Location in patent: Page/Page column 11; 12 |
| | 4-FLUORO-2-METHOXYANILINE Preparation Products And Raw materials |
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