| Company Name: |
SembCorp Shenzhenshibai a Biotechnology Co., Ltd
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| Tel: |
13412890622 |
| Email: |
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| Products Intro: |
Product Name: Ispronicline, (2S,4E)-5-(5-isopropoxypyridin-3-yl)-N-Methylpent-4-en-2-aMine
CAS:252870-53-4
Purity:98% HPLC Package:5Mg,10Mg,20Mg
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| Company Name: |
AdooQ BioScience, LLC
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| Tel: |
+1 (866) 930-6790 |
| Email: |
info@adooq.com |
| Products Intro: |
Product Name:Ispronicline
CAS:252870-53-4
Purity:98% Package:5mg;10mg;25mg;50mg;100mg;250mg;500mg;1g
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ispronicline manufacturers
- Ispronicline
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- $36.00 / 5mg
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2026-01-09
- CAS:252870-53-4
- Min. Order:
- Purity: 99.16%
- Supply Ability: 10g
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| | ispronicline Basic information |
| Product Name: | ispronicline | | Synonyms: | ispronicline;Ispronicline, (2S,4E)-5-(5-isopropoxypyridin-3-yl)-N-Methylpent-4-en-2-aMine;Ispronicline(TC-1734, AZD-3480);(2S,4E)-5-(5-isopropoxypyridin-3-yl)-N-Methylpent-4-en-2-aMine;(E,2S)-N-methyl-5-(5-propan-2-yloxypyridin-3-yl)pent-4-en-2-amine;(2S,4E)-N-methyl-5-(5-isopropoxy-3-pyridyl)-4-penten-2-amine;AZD-3480) galactaric acid salt;Ispronicline (TC-1734 | | CAS: | 252870-53-4 | | MF: | C14H22N2O | | MW: | 234.34 | | EINECS: | | | Product Categories: | | | Mol File: | 252870-53-4.mol |  |
| | ispronicline Chemical Properties |
| Boiling point | bp0.5 90-100° | | density | 0.977±0.06 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | DMSO : 100 mg/mL (426.73 mM; Need ultrasonic) | | form | Liquid | | pka | 10.03±0.10(Predicted) | | color | Colorless to light yellow |
| | ispronicline Usage And Synthesis |
| Uses | Treatment of cognitive and memory disorders
(neuronal nicotinic receptor partial agonist). | | in vivo | Ispronicline (10-20 mg/kg; s.c.) induces c-Fos expression in selective regions of the rat forebrain[1].
Ispronicline pharmacokinetics (half-life of 2 h in rats) contrasts with the long-lasting improvement of working memory (18 h to 2 d)[2]. | Animal Model: | Male Wistar rats weighting 180-200 g[1] | | Dosage: | 10 and 30 mg/kg | | Administration: | s.c. | | Result: | Induced c-Fos in medial paraventricular nucleus of hypothalamus. Treatment with 30 mg/kg ispronicline, but not 10 mg/kg, increased the number of c-Fos immunoreactive cells significantly as compared to controls within the medial parvocellular part of paraventricular nucleus (PVN).
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| | ispronicline Preparation Products And Raw materials |
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