MMP-12 (C-Term) Rabbit Monoclonal Antibody (Clone RM381)

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MMP-12 (C-Term) Rabbit Monoclonal Antibody (Clone RM381) Suppliers list
Company Name: Cayman Chemical Company  
Tel: 800-364-9897
Email: sales@caymanchem.com
Company Name: Shenzhen Campbell Biotechnology Co., Ltd.  
Tel: 18028747627
Email:
MMP-12 (C-Term) Rabbit Monoclonal Antibody (Clone RM381) Basic information
Product Name:MMP-12 (C-Term) Rabbit Monoclonal Antibody (Clone RM381)
Synonyms:MMP-12 (C-Term) Rabbit Monoclonal Antibody (Clone RM381)
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MMP-12 (C-Term) Rabbit Monoclonal Antibody (Clone RM381) Structure
MMP-12 (C-Term) Rabbit Monoclonal Antibody (Clone RM381) Chemical Properties
Safety Information
MSDS Information
MMP-12 (C-Term) Rabbit Monoclonal Antibody (Clone RM381) Usage And Synthesis
DescriptionMatrix metalloproteinase-12 (MMP-12) is a zinc-dependent metalloproteinase and member of the MMP protein family, which has roles in extracellular matrix (ECM) degradation.1 It is composed of an N-terminal proenzyme domain, a catalytic domain that contains the zinc-binding motif, and a hemopexin-like C-terminal domain. MMP-12 is a secreted protease expressed by macrophages. It is activated by the loss of the N-terminal proenzyme domain, and this active enzyme is further processed to mature MMP-12 via loss of the C-terminal domain. Levels of MMP-12 are increased in sputum from patients with chronic obstructive pulmonary disease (COPD).2 Plasma levels of MMP-12 are increased and positively associated with atherosclerosis and adverse coronary events in patients with type 2 diabetes mellitus.3 Tumor levels of MMP-12 are positively correlated with tumor size and poor overall survival in patients with hepatocellular carcinoma.4 Cayman’s MMP-12 (C-Term) Rabbit Monoclonal Antibody (Clone RM381) can be used for immunohistochemistry (IHC) and Western blot (WB) applications.WARNING This product is not for human or veterinary use.
MMP-12 (C-Term) Rabbit Monoclonal Antibody (Clone RM381) Preparation Products And Raw materials
Tag:MMP-12 (C-Term) Rabbit Monoclonal Antibody (Clone RM381) Related Product Information
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