1-(4-Methylbenzyl)piperazine

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1-(4-Methylbenzyl)piperazine Basic information
Product Name:1-(4-Methylbenzyl)piperazine
Synonyms:BUTTPARK 36\08-62;ART-CHEM-BB B004004;AKOS BBS-00003645;AKOS B004004;TIMTEC-BB SBB003648;1-(4-Methylbenzyl)piperazine
CAS:435345-17-8
MF:C12H18N2
MW:190.28
EINECS:
Product Categories:
Mol File:435345-17-8.mol
1-(4-Methylbenzyl)piperazine Structure
1-(4-Methylbenzyl)piperazine Chemical Properties
Melting point 37-41 °C(lit.)
Fp 205 °F
Safety Information
Hazard Codes Xi
Risk Statements 37/38-41
Safety Statements 26-39
WGK Germany 2
MSDS Information
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SigmaAldrich English
1-(4-Methylbenzyl)piperazine Usage And Synthesis
Uses1-(4-Methylbenzyl)piperazine is a useful synthetic intermediate in the synthesis of 3-Desmethyl 4-Methyl Meclizine Dihydrochloride (D291930); a metabolite of Meclizine (M202700, 2HCl monohydrate) which is an antiemetic. 1-(4-Methylbenzyl)piperazine is also used in the synthesis of inhibitors of acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE).
1-(4-Methylbenzyl)piperazine Preparation Products And Raw materials
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Meclozine 1-(3-Methylbenzyl)piperazine 1-(4-Methylbenzyl)piperazine 1-(2-Methylbenzyl)piperazine 1-(3-Methylbenzyl)piperazine-d8,1-(m-Methylbenzyl)piperazine-d8,N-(m-Methylbenzyl)piperazine-d8 1-(m-methylbenzyl)piperazine dihydrochloride 1-(2-Methylbenzyl)piperazine 1-(Chloroacetyl)-4-(2-methylbenzyl)piperazine hydrochloride 1-(2-fluorobenzyl)-4-(3-methylbenzyl)piperazine 1-(3-fluorobenzyl)-4-(3-methylbenzyl)piperazine 1-(4-methoxybenzoyl)-4-(3-methylbenzyl)piperazine 1-(3,4-dimethoxybenzoyl)-4-(3-methylbenzyl)piperazine 1-(3,5-dimethoxybenzoyl)-4-(4-methylbenzyl)piperazine 1-Propyl-4-(2-Methylbenzyl)Piperazine 1-Butyl-4-(2-Methylbenzyl)Piperazine 1-Hexyl-4-(2-Methylbenzyl)Piperazine 1-(4,5-Dimethoxy-2-methylbenzyl)piperazine 1-(4-Methylbenzyl)piperazine dihydrochloride