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| | 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine-N-(carboxyfluorescein) Basic information |
| Product Name: | 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine-N-(carboxyfluorescein) | | Synonyms: | 1,2-Dioleoyl-sn-glycero-3-phospho-(N-carboxyfluorescein)ethanolamine;18:1 PE CF, Phosphatidylethanolamine, dioleoyl, N-carboxyfluorescein;Phosphatidylethanolamine, dioleoyl, N-carboxyfluorescein;1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine-N-(carboxyfluorescein) Ammonium Salt;18:1 PE CF;18:1 PE CF (ammonium salt);1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine-N-(carboxyfluorescein) | | CAS: | 799268-49-8 | | MF: | C58H86NO14P | | MW: | 1052.28 | | EINECS: | | | Product Categories: | | | Mol File: | Mol File |  |
| | 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine-N-(carboxyfluorescein) Chemical Properties |
| storage temp. | −20°C | | form | solution |
| Safety Statements | 22-24/25 | | WGK Germany | 3 | | Storage Class | 6.1C - Combustible acute toxic Cat.3 toxic compounds or compounds which causing chronic effects | | Hazard Classifications | Acute Tox. 3 Inhalation Acute Tox. 4 Oral Carc. 2 Eye Irrit. 2 Repr. 2 Skin Irrit. 2 STOT RE 1 Oral STOT SE 3 |
| | 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine-N-(carboxyfluorescein) Usage And Synthesis |
| Uses | 18:1 PE CF may be used:
- to spike human serum
- to prepare concentrated lipid mix, PC:PE:fluoPE to assess basal binding properties and PC:PE:fluoPE:PIP to assess specific binding properties of the protein to each phosphoinositides (PIP)
- to prepare the large unilamellar vesicles (LUVs)
- in the preparation of fluorescent phosphoinositidecontaining liposomes
- for fluorescent labeling of total lipids to the initial liposome formulation mixture
- in the formulation of pegylated magneto-liposomes (MLs) and transferrin (Tf) embedding
| | Biological Activity | Phosphatidylethanolamine controls the membrane fluidity in eukaryotic cells. Phosphoethanolamine (PHOS) has the ability to repress tumour growth both in vitro and in vivo. It possesses anticarcinogenic effects. It can also prevent the mRNA expression of cyclin D1 and VEGFR1 (vascular endothelial growth factor receptor 1). |
| | 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine-N-(carboxyfluorescein) Preparation Products And Raw materials |
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