5-METHOXY-2-(1H-PYRROL-1-YL)ANILINE

5-METHOXY-2-(1H-PYRROL-1-YL)ANILINE Suppliers list
Company Name: Alchem Pharmtech,Inc.
Tel: 8485655694
Email: sales@alchempharmtech.com
Products Intro: Product Name:5-Methoxy-2-(1H-pyrrol-1-yl)aniline
CAS:59194-26-2
Purity:97+% Package:1g;10g;100g;;1kg Remarks:Z-51478
Company Name: CONIER CHEM AND PHARMA LIMITED
Tel: +8618523575427
Email: sales@conier.com
Products Intro: CAS:59194-26-2
Purity:0.99 Package:1kg
Company Name: Blocksynth Pharmaceutical Technology Co.,Ltd
Tel: 0086-19817745290; +8619817745290
Email: bd@blocksynth.com
Products Intro: Product Name:5-METHOXY-2-(1H-PYRROL-1-YL)ANILINE
CAS:59194-26-2
Purity:98% Package:25KG;USD
Company Name: Aladdin Scientific
Tel:
Email: tp@aladdinsci.com
Products Intro: Product Name:5-Methoxy-2-(1h-pyrrol-1-yl)aniline
CAS:59194-26-2
Purity:95% Package:$39.9/250mg;$102.9/1g;$390.9/5g;Bulk package Remarks:95%
Company Name: Amadis Chemical Company Limited
Tel: 571-89925085
Email: sales@amadischem.com
Products Intro: Product Name:5-Methoxy-2-(1H-pyrrol-1-yl)aniline
CAS:59194-26-2
Purity:0.97 Package:mgs,gs,kgs Remarks:A869248
5-METHOXY-2-(1H-PYRROL-1-YL)ANILINE Basic information
Product Name:5-METHOXY-2-(1H-PYRROL-1-YL)ANILINE
Synonyms:5-Mehoxy-2-(1H-pyrrol-1-yl)aniline;1-(2-Amino-4-methoxyphenyl)-1H-pyrrole;5-methoxy-2-(1H-pyrrol-1-yl)aniline (en);5-methoxy-2-(1H-pyrrol-1-yl)aniline(SALTDATA: 1HCl 0.5H2O);5-Methoxy-2-(1H-pyrrol-1-yl)benzenaMine;5-Methoxy-2-(1H-pyrrol-1-yl);5-METHOXY-2-(1H-PYRROL-1-YL)ANILINE;Benzenamine, 5-methoxy-2-(1H-pyrrol-1-yl)-
CAS:59194-26-2
MF:C11H12N2O
MW:188.23
EINECS:
Product Categories:
Mol File:59194-26-2.mol
5-METHOXY-2-(1H-PYRROL-1-YL)ANILINE Structure
5-METHOXY-2-(1H-PYRROL-1-YL)ANILINE Chemical Properties
Melting point 41-43°C
Boiling point 345.3±32.0 °C(Predicted)
density 1.13±0.1 g/cm3(Predicted)
storage temp. 2-8°C(protect from light)
pka2.05±0.11(Predicted)
Safety Information
Risk Statements 36/37/38
Safety Statements 26-36/37/39
HazardClass IRRITANT
HS Code 2933998090
MSDS Information
5-METHOXY-2-(1H-PYRROL-1-YL)ANILINE Usage And Synthesis
Synthesis
1-(4-methoxy-2-nitrophenyl)pyrrole

59194-25-1

5-METHOXY-2-(1H-PYRROL-1-YL)ANILINE

59194-26-2

General procedure for the synthesis of 5-methoxy-2-(1H-pyrrol-1-yl)aniline from 1-(4-methoxy-2-nitrophenyl)-1H-pyrrole: a methanolic (10 mL) suspension of 1-(4-methoxy-2-nitrophenyl)-1H-pyrrole (3 mmol) and palladium carbon (10%, 60 mg) was stirred for 5 hours under the atmosphere of hydrogen balloon. Upon completion of the reaction, the black solid was removed by filtration and the filtrate was concentrated to afford the crude product of 5-methoxy-2-(1H-pyrrol-1-yl)aniline. The crude product was purified by fast silica gel column chromatography (eluent: ethyl acetate-hexane, gradient to 1:4) to afford the target product as a light yellow oil (97% yield).1H NMR (400 MHz, CDCl3) δ 7.13-7.09 (m, 1H), 6.83-6.82 (m, 2H), 6.40-6.37 (m, 4H), and 3.84 (s, 3H); 13C NMR (100 MHz, CDCl3) δ 159.9, 143.4, 128.2, 122.1, 121.2, 109.2, 103.6, 101.1, 55.4.

References[1] Journal of Medicinal Chemistry, 2016, vol. 59, # 10, p. 4511 - 4525
[2] Patent: WO2017/149493, 2017, A1. Location in patent: Page/Page column 0150; 0151
[3] Journal of Medicinal Chemistry, 2004, vol. 47, # 8, p. 1997 - 2009
[4] Angewandte Chemie - International Edition, 2014, vol. 53, # 52, p. 14451 - 14455
[5] Angew. Chem., 2014, vol. 126, # 52, p. 14679 - 14683,5
5-METHOXY-2-(1H-PYRROL-1-YL)ANILINE Preparation Products And Raw materials
Raw materials1-(4-methoxy-2-nitrophenyl)pyrrole-->Activated carbon-->Methanol-->Hydrogen-->Palladium
Tag:5-METHOXY-2-(1H-PYRROL-1-YL)ANILINE(59194-26-2) Related Product Information
5-METHOXY-BENZO[B]THIOPHENE-2-CARBOXYLIC ACID 5-Methoxyisoindoline hydrochloride 5-METHOXY-2-METHYLBENZALDEHYDE 5-METHOXYPYRAZINE-2-CARBOXYLIC ACID 5-METHOXY-2,3-DIHYDRO-ISOINDOL-1-ONE 5-Methoxybenzofuran-2-carboxylic acid 3-Methoxy-6-Amino-2-Picoline 5-Methoxybenzofuran 5-METHOXY-PYRIDIN-3-OL 5-methoxy-1-benzothiophene IMidazo[1,2-a]pyridine,5-Methoxy- 5-METHOXY-1,3-BENZOTHIAZOL-2-AMINE Ethyl 5-methoxypyrazine-2-carboxylate 5-METHOXY-2-(1H-PYRROL-1-YL)ANILINE ASISCHEM R37792 1-(4-METHOXY-2-NITROPHENYL)-1H-PYRROLE-2-CARBALDEHYDE METHYL 3-NITRO-4-(1H-PYRROL-1-YL)PHENYL ETHER 2-(2,5-DIMETHYL-1H-PYRROL-1-YL)-5-METHOXYPHENYLAMINE

  • HomePage | Member Companies | Advertising | Contact us | Previous WebSite | MSDS | CAS Index | CAS DataBase | Privacy | Terms | About Us
  • All products displayed on this website are only for non-medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.
    According to relevant laws and regulations and the regulations of this website, units or individuals who purchase hazardous materials should obtain valid qualifications and qualification conditions.
  • Copyright © 2023 ChemicalBook All rights reserved.