tert-Butyl 6-[(1E)-2-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]ethenyl]-2,2-dimethyl-1,3-dioxane-4-acetate

tert-Butyl 6-[(1E)-2-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]ethenyl]-2,2-dimethyl-1,3-dioxane-4-acetate Suppliers list
Company Name: Hangzhou ICH Biofarm Co., Ltd
Tel: +86-0571-28186870; +undefined8613073685410
Email: sales@ichemie.com
Products Intro: Product Name:tert-Butyl 6-[(1E)-2-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]ethenyl]-2,2-dimethyl-1,3-dioxane-4-acetate
CAS:289042-12-2
Purity:98% Package:1KG;|20KG;|50KG
Company Name: airuikechemical co., ltd.
Tel: +86-18353166132
Email: sales02@airuikechemical.com
Products Intro: Product Name:r-1
CAS:289042-12-2
Purity:99.9% Package:1Kg;0.00;USD|5Kg;0.00;USD|25Kg;0.00;USD
Company Name: Sinoway Industrial co., ltd.
Tel: +86-0592-5800732 +86-13806035118
Email: xie@china-sinoway.com
Products Intro: Product Name:Rosuvastatin Intermediate R1
CAS:289042-12-2
Purity:99% up by HPLC, Single impurity < 0.3%, total impu Package:1kg;|25kg
Company Name: Beijing Cooperate Pharmaceutical Co.,Ltd
Tel: 010-60279497
Email: sales01@cooperate-pharm.com
Products Intro: Product Name:1,3-Dioxane-4-acetic acid,6-[(1E)-2-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]ethenyl]-2,2-dimethyl-, 1,1-dimethylethyl ester, (4R,6S)-
CAS:289042-12-2
Purity:98% Package:100G;1KG;5KG;10KG;25KG;50KG;100KG
Company Name: Hi-Tech Chemistry Corp
Tel: 0519-86626038
Email: yuhh@hitechem.com
Products Intro: Product Name:6-[(1E)-2-[4-(4-Fluorophenyl)-6-(1 -methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]ethenyl]-2,2-dimethyl-1,3-dioxane-4-acetic acid 1,1-dimethylethyl ester
CAS:289042-12-2
tert-Butyl 6-[(1E)-2-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]ethenyl]-2,2-dimethyl-1,3-dioxane-4-acetate Basic information
Product Name:tert-Butyl 6-[(1E)-2-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]ethenyl]-2,2-dimethyl-1,3-dioxane-4-acetate
Synonyms:(4R,6S)-6-[(1E)-2-[4-(4-FLUOROPHENYL)-6-(1-METHYLETHYL)-2-[METHYL(METHYLSULFONYL)AMINO]-5-PYRIMIDINYL]ETHENYL]-2,2-DIMETHYL-1,3-DIOXANE-4-ACETIC ACID, 1,1-DIMETHYLETHYL ESTER;tert-Butyl 6-[(1E)-2-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]ethenyl]-2,2-dimethyl-1,3-dioxane-4-acetate;6-[(1E)-2-[4-(4-Fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]ethenyl]-2,2-dimethyl-1,3-dioxane-4-acetic acid 1,1-dimethylethyl ester;Rosuvastatin intermediate R-2;Tert-Butyl-(+)7-[4-(4-Fluorophenyl)-6-Isopropyl-2-(N-Methyl-N-Methyl Sulfonylamino)Pyrimidine-5-Yl]-(3r,5s)-Dioxane-(E)-6-Heptena;Tert-butyl-(+)7-[4-(4-fluorophenyl)-6-isopropyl-2-(n-methyl,n-methyl sulphonyl amino) pyrimidine-5-yl]-(3r-5s)-dioxane-(e)-6 heptane;Tert-butyl –(+)7-[4-(4-fluorophenyl)-6-lsopropyl -2-(N-methylsulfonylamino)-pyrlmidine-5-yl]-(3R,5S)- dioxane-(E)-6-heptenate;Tert-butyl-(+)7-[4-(4-fluorophenyl)-6-isopropyl-2-(N-methyl-N-methylsulfonylamino)pyrimidine-5-yl]-(3R,5S)-dioxane-(E)
CAS:289042-12-2
MF:C29H40FN3O6S
MW:577.71
EINECS:1806241-263-5
Product Categories:INTERMEDIATES OF ROSUVASTATIN;Chiral Reagents;Inhibitors;Intermediates;Intermediates & Fine Chemicals;Pharmaceuticals
Mol File:289042-12-2.mol
tert-Butyl 6-[(1E)-2-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]ethenyl]-2,2-dimethyl-1,3-dioxane-4-acetate Structure
tert-Butyl 6-[(1E)-2-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]ethenyl]-2,2-dimethyl-1,3-dioxane-4-acetate Chemical Properties
Melting point 153-155°C
Boiling point 673.3±65.0 °C(Predicted)
density 1.210
storage temp. Inert atmosphere,2-8°C
solubility Chloroform (Slightly), Methanol (Slightly)
form Solid
pka-0.43±0.10(Predicted)
color White to Off-White
Major Applicationpharmaceutical small molecule
InChIKeyWIFPCEOJTKZGSA-UQECUQMJSA-N
SMILESO1[C@H](/C=C/C2=C(C(C)C)N=C(N(C)S(C)(=O)=O)N=C2C2=CC=C(F)C=C2)C[C@H](CC(OC(C)(C)C)=O)OC1(C)C
CAS DataBase Reference289042-12-2(CAS DataBase Reference)
Safety Information
WGK Germany WGK 3
HS Code 2935909550
Storage Class13 - Non Combustible Solids
MSDS Information
tert-Butyl 6-[(1E)-2-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]ethenyl]-2,2-dimethyl-1,3-dioxane-4-acetate Usage And Synthesis
Chemical PropertiesWhite Solid
Uses(4R,6S)-6-[(1E)-2-[4-(4-Fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]ethenyl]-2,2-dimethyl-1,3-dioxane-4-acetic Acid 1,1-Dimethylethyl Ester (Rosuvastatin EP Impurity F) is a Rosuvastatin (R700500) intermediate as HMG-CoA reductase inhibitor.
tert-Butyl 6-[(1E)-2-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]ethenyl]-2,2-dimethyl-1,3-dioxane-4-acetate Preparation Products And Raw materials
Preparation Productstert-Butyl rosuvastatin-->(Intermediates of Rosuvastatin Calcium R-4
Tag:tert-Butyl 6-[(1E)-2-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]ethenyl]-2,2-dimethyl-1,3-dioxane-4-acetate(289042-12-2) Related Product Information
VINYL PROPIONATE 4-(4-CHLORO-BENZYLOXY)-PHENYLAMINE Basic Violet 1 1-BUTEN-3-YNE Methanol Triethoxyvinylsilane Paraquat dichloride Methylparaben N-Vinyl-2-pyrrolidone Methyl acetate Methyl acrylate Kresoxim-methyl tert-Butyl rosuvastatin Pitavastatin Impurity 8 Rosuvastatin Impurity 4 Acetonitrile Ethyl propionylacetate Methyl