tert-butyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)piperidine-1-carboxylate

tert-butyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)piperidine-1-carboxylate Suppliers list

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Products Intro:	Product Name:tert-butyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)piperidine-1-carboxylate CAS:1048970-17-7 Purity:99% Package:25KG;3USD\|5KG;6USD\|1KG;9USD

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Products Intro:	Product Name:N-Boc-piperidine-4-boronic acid pinacol ester CAS:1048970-17-7 Purity:97%(Min,HPLC) Package:100g;1kg;5kg,10kg,25kg,50kg

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Products Intro:	Product Name:tert-butyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)piperidine-1-carboxylate CAS: 1048970-17-7 Purity:99% Package:1KG;7USD

Company Name:	Accela ChemBio Inc.
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Products Intro:	Product Name:N-Boc-piperidine-4-boronic Acid Pinacol Ester CAS:1048970-17-7 Purity:>=97% Package:0.25g;1g;5g;10g;25g;100g;500g

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Products Intro:	Product Name:tert-Butyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)piperidine-1-carboxylate CAS:1048970-17-7 Purity:97+% Package:1g;10g;100g;;1kg Remarks:Z-56368

tert-butyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)piperidine-1-carboxylate manufacturers

tert-butyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)piperidine-1-carboxylate Basic information

Product Name:	tert-butyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)piperidine-1-carboxylate
Synonyms:	1-BOC-PIPERIDINE-4-BORONIC ACID PINACOL ESTER;TERT-BUTOXYCARBONYLPIPERIDINE-4-BORONIC ACID, PINACOL ESTER;N-Boc-piperidine-4-boronic acid pinacol ester;Tert-butyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)piperidin-1-carboxylate;1-Piperidinecarboxylic acid, 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-, 1,1-dimethylethyl ester;1-(tert-Butoxycarbonyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)piperidine, tert-Butyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)piperidine-1-carboxylate;Piperidine-4-boronic acid, pinacol ester, N-BOC protected 97%;tert-butyl 4-(tetraMethyl-1,3,2-dioxaborolan-2-yl)piperidine-1-carboxylate
CAS:	1048970-17-7
MF:	C16H30BNO4
MW:	311.22
EINECS:
Product Categories:	Alkyl;Organoborons
Mol File:	1048970-17-7.mol

tert-butyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)piperidine-1-carboxylate Chemical Properties

Melting point	60-65°C
Boiling point	358.8±35.0 °C(Predicted)
density	1.03
storage temp.	2-8°C
pka	-1.07±0.40(Predicted)
form	solid
color	White
InChI	1S/C16H30BNO4/c1-14(2,3)20-13(19)18-10-8-12(9-11-18)17-21-15(4,5)16(6,7)22-17/h12H,8-11H2,1-7H3
InChIKey	IBLQMWKHENBVJE-UHFFFAOYSA-N
SMILES	CC(C)(C)OC(=O)N1CCC(CC1)B2OC(C)(C)C(C)(C)O2
CAS DataBase Reference	1048970-17-7

Safety Information

MSDS Information

tert-butyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)piperidine-1-carboxylate Usage And Synthesis

Uses	1-Boc-piperidin-4-ylboronic acid, pinacol ester
Synthesis	375853-82-0 1048970-17-7 General procedure for the synthesis of 1-N-tert-butoxycarbonylpiperidine-4-boronic acid pinacol ester from 1,2,3,6-tetrahydro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine: method 4: general conditions for the reduction of tetrahydropyridines to piperidines in the presence of boronic acid ester: the boronic acid ester was dissolved in a mixed solvent of ethyl acetate and methanol (1:1 v/v) , with a final borate concentration of 0.4 M) in a mixture of ethyl acetate and methanol, followed by the addition of palladium hydroxide (0.35 equiv). The reaction mixture was stirred under hydrogen atmosphere for 14 hours. Upon completion of the reaction, the reaction mixture was filtered and concentrated in vacuum to give the target piperidine product in quantitative yield. Example 8: Piperidine 8 was prepared from compound 1 in a two-step reaction using Method 4, followed by deprotection of pinacol esters using Method 2. [M-H] = 228.2 m/z. activity: b
References	[1] Patent: WO2010/118159, 2010, A1. Location in patent: Page/Page column 64-65; 67-68

tert-butyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)piperidine-1-carboxylate Preparation Products And Raw materials

Raw materials	1-Boc-piperidine-->PIPERIDINE-4-BORONIC ACID-->4-Pyridineboronic acid pinacol ester-->N-BOC-piperidine-4-carboxylic acid-->2,2'-Bis-1,3,2-benzodioxaborole-->TETRAHYDROXYDIBORON-->1-N-BOC-4-BROMOPIPERIDINE-->Di-tert-butyl dicarbonate-->CATECHOLBORANE-->Pinacol
Preparation Products	tert-butyl 4-(1H-indol-5-yl)piperidine-1-carboxylate

Tag:tert-butyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)piperidine-1-carboxylate(1048970-17-7) Related Product Information

2-Cyclopropyl-4-(4-fluorophenyl)-quinolyl-3-methanol Deionized water N,N'-Ethylenebis(stearamide) N-ACETYLLACTOSAMINE tert-butyl 4-broMo-5,6-dihydropyridine-1(2H)-carboxylate tert-butyl 4-(2-tosylhydrazono)piperidine-1-carboxylate tert-Butyl 3-Methyl-1H-pyrazole-1-carboxylate tert-butyl 4-(5-isopropoxy-2-methyl-4-nitrophenyl)piperidine-1-carboxylate tert-butyl 4-(4-aMino-5-isopropoxy-2-Methylphenyl)piperidine-1-carboxylate Sulfanilamide TERT-BUTYL 4-(3-BROMOBENZYL)PIPERAZINE-1-CARBOXYLATE 1-N-BOC-4-(4-CHLOROPHENYL)PIPERIDINE tert-butyl 4-(4-iodopyridin-2-yl)piperazine-1-carboxylate tert-Butyl 4-bromo-3,5-dimethyl-1H-pyrazole-1-carboxylate 1-Piperidinecarboxylic acid, 4-(4-methylphenyl)-, 1,1-dimethylethyl ester tert-butyl 4-(5-chloro-2-hydroxyphenyl)-1H-pyrazole-1-carboxylate Boronic acid, (1-methyl-4-piperidinyl)- (9CI) tert-butyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)piperidine-1-carboxylate