N-[(1R)-5-(1,1-Dimethylethyl)-2,3-dihydro-1H-inden-1-yl]-N'-1H-indazol-4-ylurea

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N-[(1R)-5-(1,1-Dimethylethyl)-2,3-dihydro-1H-inden-1-yl]-N'-1H-indazol-4-ylurea Suppliers list
Company Name: CONIER CHEM AND PHARMA LIMITED
Tel: +8618523575427
Email: sales@conier.com
Products Intro: Product Name:n-(5-tert-butylindan-1-yl)-n'-(1h-indazol-4-yl)urea
CAS:808756-71-0
Purity:99% Package:1kg
Company Name: TargetMol Chemicals Inc.
Tel: +1-781-999-5354; +17819995354
Email: marketing@targetmol.com
Products Intro: Product Name:ABT 102
CAS:808756-71-0
Purity:99.72% Package:1mg;117USD|5mg;262USD|10mg;388USD
Company Name: BOC Sciences
Tel: 16314854226; +16314854226
Email: inquiry@bocsci.com
Products Intro: Product Name:ABT-102
CAS:808756-71-0
Purity:98% Remarks:Please reach out to us for more information about custom solutions.
Company Name: TargetMol Chemicals Inc.
Tel: +1-781-999-5354;
Email: support@targetmol.com
Products Intro: Product Name:ABT 102；ABT-102;CHEMBL398338;ABT102
CAS:808756-71-0
Package:1 mg；10 mg；100 mg；200 mg；25 mg；5 mg；50 mg Remarks:REAGENT;FOR LABORATORY USE ONLY
Company Name: Shanghai Synchem Pharma Co., ltd  
Tel: 21-619849051-1 18521059765
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Products Intro: Product Name:N-[(1R)-5-(1,1-Dimethylethyl)-2,3-dihydro-1H-inden-1-yl]-N'-1H-indazol-4-ylurea
CAS:808756-71-0
Purity:95%+

N-[(1R)-5-(1,1-Dimethylethyl)-2,3-dihydro-1H-inden-1-yl]-N'-1H-indazol-4-ylurea manufacturers

  • ABT 102
  • ABT 102 pictures
  • $117.00
  • 2026-04-20
  • CAS:808756-71-0
  • Purity: 99.53%
  • Supply Ability: 10g
N-[(1R)-5-(1,1-Dimethylethyl)-2,3-dihydro-1H-inden-1-yl]-N'-1H-indazol-4-ylurea Basic information
Product Name:N-[(1R)-5-(1,1-Dimethylethyl)-2,3-dihydro-1H-inden-1-yl]-N'-1H-indazol-4-ylurea
Synonyms:N-[(1R)-5-(1,1-Dimethylethyl)-2,3-dihydro-1H-inden-1-yl]-N'-1H-indazol-4-ylurea;ABT-102;1-[(1R)-5-tert-butyl-2,3-dihydro-1H-inden-1-yl]-3-(1H-indazol-4-yl)urea;N-(5-tert-Butylindan-1-yl)-N'-(1H-indazol-4-yl)urea;ABT-102 (ABT102);CHEMBL398338;Urea, N-[(1R)-5-(1,1-dimethylethyl)-2,3-dihydro-1H-inden-1-yl]-N'-1H-indazol-4-yl-;ABT 102, 10 mM in DMSO
CAS:808756-71-0
MF:C21H24N4O
MW:348.44146
EINECS:
Product Categories:
Mol File:808756-71-0.mol
N-[(1R)-5-(1,1-Dimethylethyl)-2,3-dihydro-1H-inden-1-yl]-N'-1H-indazol-4-ylurea Structure
N-[(1R)-5-(1,1-Dimethylethyl)-2,3-dihydro-1H-inden-1-yl]-N'-1H-indazol-4-ylurea Chemical Properties
Boiling point 529.5±42.0 °C(Predicted)
density 1.24
pka13.04±0.20(Predicted)
Safety Information
MSDS Information
N-[(1R)-5-(1,1-Dimethylethyl)-2,3-dihydro-1H-inden-1-yl]-N'-1H-indazol-4-ylurea Usage And Synthesis
UsesABT-102 is a potent and highly selective Vanilloid Receptor (TRPV1) receptor antagonist. ABT-102 potently and reversibly increases heat pain thresholds and reduced painfulness of suprathreshold oral/cutaneous heat. ABT-102 reduces nociceptive responses of animals in models of inflammatory, bone cancer, postoperative, and osteoarthritic pain[1][2].
IC 50TRPV1
References[1] Lukin K, et al. Development of a Large Scale Asymmetric Synthesis of Vanilloid Receptor (TRPV1) Antagonist ABT-102. Organic Process Research & Development, 2007, 11(3):578-584.
[2] Rowbotham MC, et al. Oral and cutaneous thermosensory profile of selective TRPV1 inhibition by ABT-102 in a randomized healthy volunteer trial. Pain. 2011 May;152(5):1192-1200. DOI:10.1016/j.pain.2011.01.051
N-[(1R)-5-(1,1-Dimethylethyl)-2,3-dihydro-1H-inden-1-yl]-N'-1H-indazol-4-ylurea Preparation Products And Raw materials
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