6'-Dimethyl-4'-(N-succinimidyloxycarbonyl)phenyl-10-methyl-acridinium-9-carboxylate methosulfate (DMAE-NHS) manufacturers
- ME-DMAE-NHS
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2026-05-29
- CAS:115853-74-2
- Min. Order: 10mg
- Purity: 98.0%
- Supply Ability: 100g/month
- DMAE-NHS
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- $27.00
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2023-08-03
- CAS:115853-74-2
- Min. Order: 10mg
- Purity: ＞98%
- Supply Ability: 10g
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| | 6'-Dimethyl-4'-(N-succinimidyloxycarbonyl)phenyl-10-methyl-acridinium-9-carboxylate methosulfate (DMAE-NHS) Basic information |
| | 6'-Dimethyl-4'-(N-succinimidyloxycarbonyl)phenyl-10-methyl-acridinium-9-carboxylate methosulfate (DMAE-NHS) Chemical Properties |
| Melting point | 228-230℃ | | storage temp. | -20°C | | form | liquid | | InChIKey | YFWUSGGASJSGPZ-UHFFFAOYSA-M | | SMILES | C1C2=C([N+](C)=C3C(=C2C(OC2=C(C)C=C(C(ON4C(=O)CCC4=O)=O)C=C2C)=O)C=CC=C3)C=CC=1.S([O-])(OC)(=O)=O |
| | 6'-Dimethyl-4'-(N-succinimidyloxycarbonyl)phenyl-10-methyl-acridinium-9-carboxylate methosulfate (DMAE-NHS) Usage And Synthesis |
| Uses | Novel acridinium esters are disclosed that are useful, either alone or when incorporated into liposomes, as chemiluminescent agents in binding assays. | | Uses | Heterobifunctional crosslinker enabling the connection of an azide containing compound or biomolecule to one with a primary amine. The succinimidyl ester group will react preferentially with primary amines to form a covalent adduct and the terminal alkyne will react with azides via copper-catalyzed 1,3-dipolar cycloaddition click chemistry. The hydrophilic PEG spacer adds to the water solubility of this reagent, allowing for easy modification amine containing biomolecules such as antibodies, proteins and peptides with the terminal alkyne. The PEG spacer also reduces aggregation of modified proteins stored in solution by adding hydrophilic character. | | reaction suitability | reaction type: click chemistry
reagent type: cross-linking reagent |
| | 6'-Dimethyl-4'-(N-succinimidyloxycarbonyl)phenyl-10-methyl-acridinium-9-carboxylate methosulfate (DMAE-NHS) Preparation Products And Raw materials |
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