- p-nitrobenzoic acid
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- $1.70
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2026-10-13
- CAS:62-23-7
- Min. Order: 1000kg
- Purity: 99%
- Supply Ability: 50 tons
- P-Nitrobenzoic acid
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2026-10-11
- CAS:62-23-7
- Min. Order: 1000kg
- Purity: 99.9%
- Supply Ability: 10000ton
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| | 4-Nitrobenzoic acid Basic information |
| | 4-Nitrobenzoic acid Chemical Properties |
| Melting point | 237-240 °C(lit.) | | Boiling point | 295.67°C (rough estimate) | | density | 1.61 | | bulk density | 700kg/m3 | | refractive index | 1.6280 (estimate) | | Fp | 237 °C | | storage temp. | Store below +30°C. | | solubility | 0.42g/l | | pka | 3.41(at 25℃) | | form | Crystalline Powder | | color | Light yellow | | PH | 3.1 (0.42g/l, H2O, 20℃)(saturated solution) | | Water Solubility | <0.1 g/100 mL at 26 ºC | | Merck | 14,6589 | | BRN | 973593 | | Specific Activity | 50-60 mCi/mmol | | Concentration | 0.1 mCi/ml | | Solvent | Ethanol | | Henry's Law Constant | 3.2×103 mol/(m3Pa) at 25℃, Abraham and Jr. (2019) | | Stability: | Stable. Combustible. Incompatible with strong oxidizing agents, cyanides, strong bases. | | InChI | 1S/C7H5NO4/c9-7(10)5-1-3-6(4-2-5)8(11)12/h1-4H,(H,9,10) | | InChIKey | OTLNPYWUJOZPPA-UHFFFAOYSA-N | | SMILES | OC(=O)c1ccc(cc1)[N+]([O-])=O | | LogP | 1.890 | | CAS DataBase Reference | 62-23-7(CAS DataBase Reference) | | NIST Chemistry Reference | Benzoic acid, 4-nitro-(62-23-7) | | EPA Substance Registry System | p-Nitrobenzoic acid (62-23-7) |
| Hazard Codes | Xn | | Risk Statements | 22-41-36 | | Safety Statements | 26-39-24/25 | | WGK Germany | 1 | | RTECS | DH5075000 | | TSCA | TSCA listed | | HS Code | 29163900 | | Storage Class | 11 - Combustible Solids | | Hazard Classifications | Acute Tox. 4 Oral
Carc. 2
Eye Irrit. 2
Muta. 2
Repr. 2
Skin Irrit. 2 | | Hazardous Substances Data | 62-23-7(Hazardous Substances Data) | | Toxicity | LD50 orally in Rabbit: 1960 mg/kg |
| | 4-Nitrobenzoic acid Usage And Synthesis |
| Chemical Properties | light yellow crystalline powder | | Uses | 4-Nitrobenzoic Acid is used in the synthesis of anti-Trypanosoma cruzi agents in the treatment of chagas disease. | | Production Methods | p-Nitrobenzoic acid is produced commercially by the oxidation of 4-nitrotoluene with molecular oxygen. Oxidation with 15 % nitric acid at 175 ℃ produces the acid in 88.5 % yield. An interesting method involves the nitration and subsequent oxidation of polystyrene. This method uses the steric hindrance of the polymer chain to improve the para to ortho ratio of the product. | | Definition | ChEBI: A nitrobenzoic acid having the nitro group at the 4-position. | | Synthesis Reference(s) | Tetrahedron Letters, 26, p. 2387, 1985 DOI: 10.1016/S0040-4039(00)94834-2
Journal of the American Chemical Society, 72, p. 5012, 1950 DOI: 10.1021/ja01167a051 | | General Description | Odorless pale yellow crystals. | | Air & Water Reactions | Insoluble in water. | | Reactivity Profile | p-Nitrobenzoic acid is incompatible with strong oxidizers. p-Nitrobenzoic acid is also incompatible with strong bases (potassium hydroxide). p-Nitrobenzoic acid may react with cyanides. | | Fire Hazard | p-Nitrobenzoic acid is combustible. | | Toxicology | Among various nitroaromatics, 4-nitrobenzoic acid (4-NBA) is one of the simplest and basic derivates of the explosives. Moreover, 4-NBA harms human health and causes severe water and atmosphere pollution. 4-Nitrobenzoic acid is stable, toxic, and non-biodegradable. US/Zn0 was found to degrade more than 85% of 4-nitrobenzoic acid in 30 min. There was an apparent synergistic effect between ultrasound and Zn[1-2]. | | Purification Methods | Purify it as for 3-nitrobenzoic acid above. The amide has m 201.6o (from H2O). [Beilstein 9 III 1537, 9 IV 1072.] | | References |
[1] Shan Chong. “Ultrasound/Zn0 for aqueous 4-nitrobenzoic acid degradation.” Desalination and Water Treatment 322 1 (2016): 24990–24998.
[2] Xue-Huan Xin . “A luminescent barium-based metal-organic framework: Synthesis, structure and efficient detection of 4-nitrobenzoic acid.” Inorganic Chemistry Communications 97 (2018): Pages 129-133.
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| | 4-Nitrobenzoic acid Preparation Products And Raw materials |
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