|
|
| | 1H-Pyrrole-1-carboxylic acid, 2-(aMinocarbonyl)-2,3-dihydro-, 1,1-diMethylethyl ester, (2S)- Basic information |
| Product Name: | 1H-Pyrrole-1-carboxylic acid, 2-(aMinocarbonyl)-2,3-dihydro-, 1,1-diMethylethyl ester, (2S)- | | Synonyms: | 1H-Pyrrole-1-carboxylic acid, 2-(aMinocarbonyl)-2,3-dihydro-, 1,1-diMethylethyl ester, (2S)-;(S)-Boc-2-carbaMoyl-2,3-dihydro-1H-pyrrole;(2S)-2-(Aminocarbonyl)-2,3-dihydro-1H-pyrrole-1-carboxylic acid 1,1-dimethylethyl ester;(S)-tert-butyl 2-carbaMoyl-2,3-dihydropyrrole-1-carboxylate;(S)-tert-Butyl 2-carbamoyl-2,3-dihydro-1H-pyrrole-1-carboxylate;Saxagliptin impurity I;Saxaint-T;tert-butyl (2S)-2-carbamoyl-2,3-dihydropyrrole-1-carboxylate | | CAS: | 709031-38-9 | | MF: | C10H16N2O3 | | MW: | 212.25 | | EINECS: | 615-204-0 | | Product Categories: | | | Mol File: | 709031-38-9.mol |  |
| | 1H-Pyrrole-1-carboxylic acid, 2-(aMinocarbonyl)-2,3-dihydro-, 1,1-diMethylethyl ester, (2S)- Chemical Properties |
| Boiling point | 386.5±42.0 °C(Predicted) | | density | 1.187±0.06 g/cm3(Predicted) | | storage temp. | 2-8°C | | pka | 15.57±0.20(Predicted) |
| | 1H-Pyrrole-1-carboxylic acid, 2-(aMinocarbonyl)-2,3-dihydro-, 1,1-diMethylethyl ester, (2S)- Usage And Synthesis |
| Uses | (S)-Boc-2-carbamoyl-2,3-dihydro-1H-pyrrole is an impurity of Saxagliptin (S143500), which is a potent and selective reversible inhibitor of dipeptidyl peptidase-4, which is being developed for the treatment of type 2 diabetes. It is absorbed rapidly after oral administration and has a pharmacokinetic profile compatible with once daily dosing. |
| | 1H-Pyrrole-1-carboxylic acid, 2-(aMinocarbonyl)-2,3-dihydro-, 1,1-diMethylethyl ester, (2S)- Preparation Products And Raw materials |
|