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| | 2-(5-fluoropentyl)-2-MethylMalonic acid Basic information |
| | 2-(5-fluoropentyl)-2-MethylMalonic acid Chemical Properties |
| | 2-(5-fluoropentyl)-2-MethylMalonic acid Usage And Synthesis |
| Uses | ML-10 is a small molecule apoptosis probe. Due to the presence of fluorine atoms, ML-10 can be radiolabeled with 18F isotopes and can be used for apoptosis positron emission tomography imaging studies. ML-10 is selectively taken up and accumulated in apoptotic cells, while being excluded from live or necrotic cells. In addition, the uptake of ML-10 is associated with apoptotic features such as caspase activation, Annexin-V binding, and disruption of mitochondrial membrane potential[1]. | | References | [1] Cohen A, et al. From the Gla domain to a novel small-molecule detector of apoptosis. Cell Res. 2009 May;19(5):625-37. DOI:10.1038/cr.2009.17 |
| | 2-(5-fluoropentyl)-2-MethylMalonic acid Preparation Products And Raw materials |
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